Protein: SOCS3
Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (Protein EF-10)

Gene: SOCS3
Organism: Mus musculus
Interactions: 32
UniProt ID: O35718

Gene Ontology (top 5):
GO:0001784 - phosphotyrosine residue binding
GO:0001932 - regulation of protein phosphorylation
GO:0005829 - cytosol
GO:0005942 - phosphatidylinositol 3-kinase complex
GO:0007165 - signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

193377

STAT3
Signal transducer and activator of transcription 3

7

20

Small-scale

0.951

High

193384

IL6RB
Interleukin-6 receptor subunit beta

3

20

Small-scale

0.853

High

193387

JAK2
Tyrosine-protein kinase JAK2

2

20

Small-scale

0.799

High

193382

ELOB
Elongin-B

3

11

Small-scale

0.681

High

193383

ELOC
Elongin-C

3

10

Small-scale

0.676

High

193394

CUL5
Cullin-5

3

20

Small-scale

0.664

High

69807

B1ASP2
Tyrosine-protein kinase

1

20

Small-scale

0.647

High

193376

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

20

Small-scale

0.625

High

193372

EPOR
Erythropoietin receptor

1

20

Small-scale

0.618

High

193375

FAK1
Focal adhesion kinase 1

1

20

Small-scale

0.618

High

193378

CRKL
Crk-like protein

1

20

Small-scale

0.618

High

193381

STAT6
Signal transducer and transcription activator 6

1

20

Small-scale

0.618

High

193392

NCK1
SH2/SH3 adapter protein Nck1

1

20

Small-scale

0.618

High

193374

I23O1
Indoleamine 2,3-dioxygenase 1

1

0

Small-scale

0.554

High

193373

INSR
Insulin receptor

1

20

Small-scale

0.553

High

193396

RBX2
RING-box protein 2

1

9

Small-scale

0.536

High

193397

BCL10
B-cell lymphoma/leukemia 10

1

0

Small-scale

0.493

High

193367

CSN5
COP9 signalosome complex subunit 5

1

2

Small-scale

0.479

High

193368

CSN4
COP9 signalosome complex subunit 4

1

1

Small-scale

0.479

High

193385

TFDP1
Transcription factor Dp-1

1

2

Small-scale

0.479

High

193386

RUNX2
Runt-related transcription factor 2

1

3

Small-scale

0.479

High

193388

Q80SY9
Nucleotide-binding oligomerization domain-containing protein 2

1

1

Small-scale

0.479

High

193389

SMAD3
Mothers against decapentaplegic homolog 3

1

6

Small-scale

0.479

High

193390

MAP1S
Microtubule-associated protein 1S

1

10

Small-scale

0.479

High

193393

CSN7A
COP9 signalosome complex subunit 7a

1

1

Small-scale

0.479

High

193395

KC1E
Casein kinase I isoform epsilon

1

8

Small-scale

0.479

High

193391

CSN8
COP9 signalosome complex subunit 8

1

0

Small-scale

0.458

High

193379

LEPR
Leptin receptor

1

20

Small-scale

0.457

High

193369

CSN6
COP9 signalosome complex subunit 6

1

1

Small-scale

0.437

High

193370

CASK
Kappa-casein

1

1

Small-scale

0.437

High

193371

CASB
Beta-casein

1

2

Small-scale

0.437

High

193380

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

2

Small-scale

0.437

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024