HitPredict

Interactor 1: ITA2 (P17301)
Integrin alpha-2 (CD49 antigen-like family member B) (Collagen receptor) (Platelet membrane glycoprotein Ia) (GPIa) (VLA-2 subunit alpha) (CD antigen CD49b)
Gene: ITGA2

Interactor 2: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36976175
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001618 - virus receptor activity GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0007155 - cell adhesion GO:0009986 - cell surface
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1181 Hs			1 976
+	Hs
		603753 ITA2_HUMAN (1-1181): 0: 1240: 100.00		UFO_HUMAN (294-911): 1.96e-144: 454: 24.15
+	Mm
		683102 ITA2_MOUSE (1-1181): 0: 1251: 82.22		LYN_MOUSE (607-879): 1.97e-64: 228: 42.91
+	Hs
		463322 ITA2_HUMAN (1-1181): 0: 1240: 100.00		LYN_HUMAN (607-879): 2.07e-64: 228: 42.91
+	Hs
		654935 ITA6_HUMAN (14-508): 1.83e-56: 216: 17.08		EPHA2_HUMAN (1-976): 0: 1124: 100.00
+	Hs
		710231 ITA7_HUMAN (5-512): 1.34e-56: 216: 17.38		EPHA2_HUMAN (1-976): 0: 1124: 100.00
+	Hs
		565169 ITA4_HUMAN (2-513): 1.43e-56: 215: 20.73		EPHA2_HUMAN (1-976): 0: 1124: 100.00
+	Hs
		683581 ITA3_HUMAN (2-512): 7.79e-56: 213: 18.44		EPHA2_HUMAN (1-976): 0: 1124: 100.00
+	Hs
		447987 ITAV_HUMAN (27-513): 4.21e-52: 201: 16.73		EPHA2_HUMAN (1-976): 0: 1124: 100.00
+	Hs
		439614 ITAV_HUMAN (27-513): 4.21e-52: 201: 16.73		INSR_HUMAN (281-911): 2.91e-136: 444: 24.78
+	Hs
		447957 ITAV_HUMAN (27-513): 4.21e-52: 201: 16.73		IGF1R_HUMAN (393-877): 1.45e-133: 437: 29.90
+	Hs
		463305 ITA4_HUMAN (2-513): 1.43e-56: 215: 20.73		LYN_HUMAN (607-879): 2.07e-64: 228: 42.91