HitPredict

Interactor 1: FBRL (P22087)
rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (34 kDa nucleolar scleroderma antigen) (Histone-glutamine methyltransferase) (U6 snRNA 2'-O-methyltransferase fibrillarin)
Gene: FBL

Interactor 2: DDX18 (Q9NVP1)
ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb)
Gene: DDX18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29568061, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 321 Hs			1 670
+	Hs
		603479 FBRL_HUMAN (1-321): 1.98e-177: 495: 100.00		DDX10_HUMAN (124-621): 9.53e-167: 501: 41.60
+	Hs
		603602 FBRL_HUMAN (1-321): 1.98e-177: 495: 100.00		DDX55_HUMAN (176-668): 5.77e-136: 413: 34.05
+	Hs
		571306 FBRL_HUMAN (1-321): 1.98e-177: 495: 100.00		DDX5_HUMAN (71-600): 2.27e-133: 407: 22.47
+	Sc
		549326 FBRL_YEAST (85-313): 1.1e-136: 392: 70.76		DBP4_YEAST (141-662): 8.19e-161: 483: 35.85
+	Sc
		549480 FBRL_YEAST (85-313): 1.1e-136: 392: 70.76		HAS1_YEAST (142-641): 8.13e-140: 420: 57.69
+	Hs
		603724 FBRL_HUMAN (1-321): 1.98e-177: 495: 100.00		DDX31_HUMAN (87-619): 1.02e-81: 278: 33.71
+	Hs
		603706 FBRL_HUMAN (1-321): 1.98e-177: 495: 100.00		DDX47_HUMAN (192-524): 3.3e-64: 221: 39.82
+	Hs
		603643 FBRL_HUMAN (1-321): 1.98e-177: 495: 100.00		DDX27_HUMAN (121-574): 3.56e-56: 206: 34.88
+	Sc
		549341 FBRL_YEAST (85-313): 1.1e-136: 392: 70.76		SPB4_YEAST (197-618): 1.28e-57: 207: 32.29