Interactor 1: SIN3 (P22579)
Transcriptional regulatory protein SIN3
Gene: SIN3

Interactor 2: RPD3 (P32561)
Histone deacetylase RPD3 (EC 3.5.1.98) (Transcriptional regulatory protein RPD3)
Gene: RPD3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.766

The method score is based on:

Property Details
Experiments 9150136, 9234741, 9512514, 11805826, 23878396, 11156977, 16429126, 16275642, 16286008, 16314178, 16286007, 19806189, 37968396, 36888706, 17101441, 22543816, 15141165, 11024051, 16554755, 26747610 and 3 others

more...

Identification Methods coimmunoprecipitation, affinity chromatography technology, two hybrid, tandem affinity purification, pull down, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003713 - transcription coactivator activity
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0006334 - nucleosome assembly
and 12 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1536
Sc

1 433
+ Sc
+ Sc
+ Sp
+ Ce
+ Ce
+ Hs
+ Mm
+ Dm
+ Dm
+ Hs
+ Mm
+ Hs
+ Mm
+ Sp
+ Hs
+ At
+ At
+ Hs
+ Dm
+ Mm

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Last updated: 15 Jul 2024