HitPredict

Interactor 1: PTPRA (P18052)
Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) (LCA-related phosphatase) (PTPTY-28)
Gene: PTPRA

Interactor 2: S4R1M0 (S4R1M0)
Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (T200)
Gene: Ptprc

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	12376545
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Y_phosphatase~Y_phosphatase
Common GO terms	GO:0004725 - protein tyrosine phosphatase activity GO:0016020 - membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 829 Mm			1 1130
+	Mm
		72845 PTPRS_MOUSE (5-826): 0: 893: 36.30		S4R1M0_MOUSE (1-1130): 0: 1104: 100.00
+	Mm
		611448 PTPRA_MOUSE (1-829): 0: 1013: 100.00		PTPRE_MOUSE (713-1127): 5.75e-112: 366: 23.54
+	Mm
		611443 PTPRA_MOUSE (1-829): 0: 1013: 100.00		PTPRA_MOUSE (755-1127): 2.31e-105: 352: 24.56
+	Hs
		614649 PTPRA_HUMAN (1-829): 0: 981: 89.50		PTPRE_HUMAN (713-1127): 1.17e-116: 379: 23.78
+	Hs
		614646 PTPRA_HUMAN (1-829): 0: 981: 89.50		PTPRA_HUMAN (755-1127): 1.64e-112: 371: 25.66
+	Hs
		614650 PTPRA_HUMAN (1-829): 0: 981: 89.50		PTPRG_HUMAN (746-1125): 3.57e-105: 363: 22.08
+	Mm
		883406 PTPRD_MOUSE (14-826): 0: 899: 38.14		PTPRE_MOUSE (713-1127): 5.75e-112: 366: 23.54
+	Mm
		72836 PTPRS_MOUSE (5-826): 0: 893: 36.30		PTPRE_MOUSE (713-1127): 5.75e-112: 366: 23.54
+	Mm
		59106 PTPRA_MOUSE (1-829): 0: 1013: 100.00		PTPRF_MOUSE (26-551): 3.4e-51: 200: 10.59
+	Mm
		611444 PTPRA_MOUSE (1-829): 0: 1013: 100.00		PTPRM_MOUSE (41-411): 6.53e-29: 128: 12.27
+	Mm
		611454 PTPRA_MOUSE (1-829): 0: 1013: 100.00		PTPRD_MOUSE (19-562): 7.57e-26: 118: 11.61
+	Mm
		72835 PTPRA_MOUSE (1-829): 0: 1013: 100.00		PTPRS_MOUSE (18-533): 8.82e-26: 118: 9.55
+	Hs
		522657 PTPRS_HUMAN (5-826): 0: 894: 35.86		PTPRF_HUMAN (17-527): 8.72e-50: 195: 12.59
+	Hs
		658845 PTPRD_HUMAN (14-826): 0: 894: 38.02		PTPRD_HUMAN (19-562): 1.87e-26: 119: 11.61
+	Hs
		658881 PTPRS_HUMAN (5-826): 0: 894: 35.86		PTPRD_HUMAN (19-562): 1.87e-26: 119: 11.61
+	Hs
		1102694 PTPRS_HUMAN (5-826): 0: 894: 35.86		PTPRS_HUMAN (18-562): 2.28e-25: 116: 9.36
+	Hs
		658822 PTPRS_HUMAN (5-826): 0: 894: 35.86		PTPRB_HUMAN (37-537): 3.22e-14: 79.9: 12.25