HitPredict

Interactor 1: TRX2 (P22803)
Thioredoxin-2 (Thioredoxin II) (TR-II) (Thioredoxin-1)
Gene: TRX2

Interactor 2: AHP1 (P38013)
Peroxiredoxin AHP1 (Prx) (EC 1.11.1.24) (Alkyl hydroperoxide reductase) (AHPC1) (Cytoplasmic thiol peroxidase 3) (cTPx 3) (Thiol-specific antioxidant II) (TSA II) (Thioredoxin peroxidase type II) (TPx type II) (Thioredoxin-dependent peroxiredoxin AHP1)
Gene: AHP1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.815

Property	Details
Experiments	16272220, 22474296
Identification Methods	two hybrid, affinity chromatography technology, x-ray crystallography, pull down
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Redoxin~Thioredoxin
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045454 - cell redox homeostasis
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 104 Sc			1 176
+	Sc
		606201 TRX1_YEAST (1-103): 9.82e-38: 124: 78.64		AHP1_YEAST (1-176): 1.27e-84: 248: 100.00
+	At
		1114770 TRXH3_ARATH (2-103): 2.84e-33: 113: 37.14		PRX2E_ARATH (5-176): 2.49e-62: 194: 29.55
+	Ss
		852795 THIO_SYNY3 (6-104): 1.03e-34: 116: 33.66		PRX5_SYNY3 (23-176): 1.72e-59: 185: 26.51
+	At
		667117 TRXH1_ARATH (2-104): 1.48e-35: 119: 35.85		PRX2B_ARATH (5-176): 9.54e-58: 179: 31.61
+	At
		1226366 TRXY2_ARATH (4-104): 1.41e-34: 118: 32.04		PRX2B_ARATH (5-176): 9.54e-58: 179: 31.61
+	Mm
		956717 THIOM_MOUSE (5-104): 3.85e-34: 117: 31.37		PRDX5_MOUSE (29-176): 1.12e-53: 171: 26.32
+	Ss
		852844 THIO1_SYNY3 (6-90): 2.8e-16: 69.7: 37.21		PRX5_SYNY3 (23-176): 1.72e-59: 185: 26.51