HitPredict

Interactor 1: ACTN (P18091)
Alpha-actinin, sarcomeric (F-actin cross-linking protein)
Gene: ACTN

Interactor 2: MYSP2 (P35416)
Paramyosin, short form (Miniparamyosin)
Gene: Prm

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 924 Dm			1 640
+	Hs
		555621 ACTN1_HUMAN (5-924): 0: 623: 67.50		MYH9_HUMAN (2-638): 1.09e-28: 124: 13.61
+	Dm
		432166 ACTN_DROME (1-924): 0: 628: 100.00		MYSA_DROME (3-640): 2.76e-17: 88.5: 10.31
+	Hs
		67529 ACTN1_HUMAN (5-924): 0: 623: 67.50		MYH7B_HUMAN (8-639): 3.18e-17: 88.5: 9.89
+	Hs
		224639 ACTN4_HUMAN (14-924): 0: 576: 67.29		MYH9_HUMAN (2-638): 1.09e-28: 124: 13.61
+	Hs
		67521 ACTN4_HUMAN (14-924): 0: 576: 67.29		MYH7B_HUMAN (8-639): 3.18e-17: 88.5: 9.89
+	Hs
		67532 ACTN2_HUMAN (5-924): 0: 576: 66.41		MYH7B_HUMAN (8-639): 3.18e-17: 88.5: 9.89
+	Mm
		945615 ACTN4_MOUSE (14-924): 0: 573: 67.29		MYH6_MOUSE (14-472): 1.27e-15: 83.1: 9.76
+	Hs
		772789 SPTN1_HUMAN (307-729): 5.69e-14: 79: 16.16		MYH9_HUMAN (2-638): 1.09e-28: 124: 13.61
+	Hs
		174713 SPTN2_HUMAN (197-840): 1.02e-13: 78.1: 13.23		MYH9_HUMAN (2-638): 1.09e-28: 124: 13.61
+	Hs
		772748 SPTB2_HUMAN (187-837): 5.84e-12: 72.4: 10.62		MYH9_HUMAN (2-638): 1.09e-28: 124: 13.61
+	Hs
		556923 SPTN1_HUMAN (307-729): 5.69e-14: 79: 16.16		MYH7_HUMAN (7-421): 6.51e-17: 87.3: 12.77