HitPredict

Interactor 1: SYB (P18489)
Synaptobrevin
Gene: SYB

Interactor 2: USE1 (Q9VSU7)
Vesicle transport protein USE1 (USE1-like protein)
Gene: USE1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0031201 - SNARE complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 152 Dm			1 250
+	Dm
		1263471 Q7JYX5_DROME (4-127): 3.99e-39: 133: 14.29		USE1_DROME (1-250): 9.35e-92: 272: 100.00
+	Dm
		121828 M9PGI6_DROME (3-128): 8.27e-37: 127: 16.67		USE1_DROME (1-250): 9.35e-92: 272: 100.00
+	Hs
		280358 SC22B_HUMAN (3-131): 5.15e-39: 132: 18.32		USE1_HUMAN (2-249): 7.81e-90: 267: 30.62
+	Dm
		305593 O77434_DROME (3-128): 9.32e-37: 127: 16.67		USE1_DROME (1-250): 9.35e-92: 272: 100.00
+	Hs
		192332 YKT6_HUMAN (1-101): 3.96e-33: 117: 20.79		USE1_HUMAN (2-249): 7.81e-90: 267: 30.62
+	Hs
		1154770 VAMP3_HUMAN (34-115): 1.55e-28: 102: 60.98		USE1_HUMAN (2-249): 7.81e-90: 267: 30.62
+	Hs
		278572 VAMP4_HUMAN (30-115): 4.73e-27: 100: 30.23		USE1_HUMAN (2-249): 7.81e-90: 267: 30.62
+	Hs
		328752 VAMP5_HUMAN (44-114): 6.87e-19: 78.6: 40.85		USE1_HUMAN (2-249): 7.81e-90: 267: 30.62