HitPredict

Interactor 1: SYB (P18489)
Synaptobrevin
Gene: SYB

Interactor 2: Q9VVX6 (Q9VVX6)
BET1 homolog (Golgi vesicular membrane-trafficking protein p18)
Gene: Bet1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNARE~Synaptobrevin
Common GO terms	GO:0005484 - SNAP receptor activity GO:0016192 - vesicle-mediated transport GO:0019905 - syntaxin binding GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 152 Dm			1 117
+	Dm
		614909 SYB_DROME (1-152): 1.12e-53: 168: 100.00		Q7JRF1_DROME (17-116): 8.59e-23: 92: 17.00
+	Dm
		1263475 Q7JYX5_DROME (4-127): 3.99e-39: 133: 14.29		Q9VVX6_DROME (1-117): 3.51e-37: 123: 100.00
+	Hs
		179768 SC22B_HUMAN (3-131): 5.15e-39: 132: 18.32		BET1_HUMAN (10-117): 1.08e-36: 122: 39.82
+	Dm
		121833 M9PGI6_DROME (3-128): 8.27e-37: 127: 16.67		Q9VVX6_DROME (1-117): 3.51e-37: 123: 100.00
+	Dm
		305598 O77434_DROME (3-128): 9.32e-37: 127: 16.67		Q9VVX6_DROME (1-117): 3.51e-37: 123: 100.00
+	Rn
		1204259 YKT6_RAT (1-101): 9.4e-34: 119: 20.79		BET1_RAT (7-117): 1.19e-36: 122: 36.94
+	Hs
		179756 YKT6_HUMAN (1-101): 3.96e-33: 117: 20.79		BET1_HUMAN (10-117): 1.08e-36: 122: 39.82
+	Mm
		205242 YKT6_MOUSE (1-101): 1.74e-33: 118: 20.79		BET1_MOUSE (7-117): 4.93e-36: 120: 36.94
+	Hs
		179853 VAMP7_HUMAN (3-112): 4.71e-31: 112: 22.32		BET1_HUMAN (10-117): 1.08e-36: 122: 39.82
+	Hs
		280356 SC22B_HUMAN (3-131): 5.15e-39: 132: 18.32		BET1L_HUMAN (20-114): 3.44e-24: 90.5: 31.25
+	Sc
		646213 SEC22_YEAST (3-129): 6.21e-37: 127: 19.38		BET1_YEAST (17-114): 7.25e-25: 93.2: 21.43
+	Hs
		249804 SC22B_HUMAN (3-131): 5.15e-39: 132: 18.32		STX10_HUMAN (18-100): 5.6e-21: 85.9: 20.48
+	Hs
		225883 SC22B_HUMAN (3-131): 5.15e-39: 132: 18.32		STX6_HUMAN (8-100): 1.41e-19: 82.4: 22.58
+	Rn
		204384 YKT6_RAT (1-101): 9.4e-34: 119: 20.79		BET1L_RAT (19-114): 1.71e-24: 91.3: 29.90
+	Sc
		646254 SEC22_YEAST (3-129): 6.21e-37: 127: 19.38		SFT1_YEAST (19-116): 2.56e-21: 82.8: 19.39
+	Hs
		192330 YKT6_HUMAN (1-101): 3.96e-33: 117: 20.79		BET1L_HUMAN (20-114): 3.44e-24: 90.5: 31.25
+	Hs
		192145 YKT6_HUMAN (1-101): 3.96e-33: 117: 20.79		STX6_HUMAN (8-100): 1.41e-19: 82.4: 22.58
+	Sc
		652916 SNC2_YEAST (18-115): 5.49e-29: 104: 29.59		BET1_YEAST (17-114): 7.25e-25: 93.2: 21.43
+	Hs
		225968 VAMP7_HUMAN (3-112): 4.71e-31: 112: 22.32		STX6_HUMAN (8-100): 1.41e-19: 82.4: 22.58
+	Rn
		1224612 VAMP1_RAT (18-120): 1.45e-31: 110: 56.31		STX6_RAT (8-101): 3e-20: 83.9: 22.34