HitPredict

Interactor 1: SYB (P18489)
Synaptobrevin
Gene: SYB

Interactor 2: Q9W1I8 (Q9W1I8)
LD03592p (Synaptosomal-associated protein 29kDa)
Gene: Snap29

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.685

Property	Details
Experiments	25551675, 15710747, 22036573, 38944040
Identification Methods	affinity chromatography technology, two hybrid, two hybrid fragment pooling approach, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000149 - SNARE binding GO:0005484 - SNAP receptor activity GO:0005886 - plasma membrane GO:0016192 - vesicle-mediated transport GO:0019905 - syntaxin binding and 1 others more... GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 152 Dm			1 284
+	Dm
		1263479 Q7JYX5_DROME (4-127): 3.99e-39: 133: 14.29		Q9W1I8_DROME (1-284): 1.63e-93: 279: 100.00
+	Dm
		121837 M9PGI6_DROME (3-128): 8.27e-37: 127: 16.67		Q9W1I8_DROME (1-284): 1.63e-93: 279: 100.00
+	Dm
		305602 O77434_DROME (3-128): 9.32e-37: 127: 16.67		Q9W1I8_DROME (1-284): 1.63e-93: 279: 100.00
+	Dm
		1489289 NSYB_DROME (37-130): 1.25e-31: 113: 68.09		Q9W1I8_DROME (1-284): 1.63e-93: 279: 100.00
+	Dm
		614942 SYB_DROME (1-152): 1.12e-53: 168: 100.00		Q9VH76_DROME (56-283): 1.03e-55: 180: 23.68
+	Dm
		614888 SYB_DROME (1-152): 1.12e-53: 168: 100.00		SNP25_DROME (51-283): 1.3e-50: 167: 21.89
+	Hs
		280081 SC22B_HUMAN (3-131): 5.15e-39: 132: 18.32		SNP29_HUMAN (42-281): 3.48e-62: 198: 30.44
+	At
		866335 VA722_ARATH (3-112): 5.63e-42: 140: 23.89		SNP33_ARATH (48-284): 8.5e-56: 183: 19.75
+	At
		1456080 VA721_ARATH (3-112): 1.09e-41: 139: 23.01		SNP33_ARATH (48-284): 8.5e-56: 183: 19.75
+	Hs
		192158 YKT6_HUMAN (1-101): 3.96e-33: 117: 20.79		SNP29_HUMAN (42-281): 3.48e-62: 198: 30.44
+	Dm
		1263461 Q7JYX5_DROME (4-127): 3.99e-39: 133: 14.29		Q9VH76_DROME (56-283): 1.03e-55: 180: 23.68
+	Hs
		343334 VAMP7_HUMAN (3-112): 4.71e-31: 112: 22.32		SNP29_HUMAN (42-281): 3.48e-62: 198: 30.44
+	Dm
		121817 M9PGI6_DROME (3-128): 8.27e-37: 127: 16.67		Q9VH76_DROME (56-283): 1.03e-55: 180: 23.68
+	Dm
		305584 O77434_DROME (3-128): 9.32e-37: 127: 16.67		Q9VH76_DROME (56-283): 1.03e-55: 180: 23.68
+	Dm
		788352 Q7JYX5_DROME (4-127): 3.99e-39: 133: 14.29		SNP25_DROME (51-283): 1.3e-50: 167: 21.89
+	Hs
		124015 VAMP7_HUMAN (3-112): 4.71e-31: 112: 22.32		SNP23_HUMAN (63-282): 2.44e-57: 184: 23.08
+	Dm
		121785 M9PGI6_DROME (3-128): 8.27e-37: 127: 16.67		SNP25_DROME (51-283): 1.3e-50: 167: 21.89
+	Dm
		1475590 NSYB_DROME (37-130): 1.25e-31: 113: 68.09		Q9VH76_DROME (56-283): 1.03e-55: 180: 23.68
+	Rn
		954438 VAMP7_RAT (3-113): 4.42e-31: 112: 22.12		SNP25_RAT (59-283): 3.29e-50: 166: 20.44
+	Sc
		646244 SEC22_YEAST (3-129): 6.21e-37: 127: 19.38		SEC9_YEAST (39-278): 8.79e-32: 125: 17.60