HitPredict

Interactor 1: S10A1 (P23297)
Protein S100-A1 (S-100 protein alpha chain) (S-100 protein subunit alpha) (S100 calcium-binding protein A1)
Gene: S100A1

Interactor 2: NAC1 (P32418)
Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1)
Gene: SLC8A1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy, isothermal titration calorimetry
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 94 Hs			1 973
+	Hs
		685156 S10AB_HUMAN (2-92): 6.83e-36: 119: 41.76		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		638928 S100P_HUMAN (3-92): 3.73e-33: 111: 54.44		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689702 S10AA_HUMAN (1-91): 5.26e-33: 111: 48.35		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689707 S100Z_HUMAN (1-93): 4.63e-33: 111: 58.07		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		642918 S10A4_HUMAN (1-90): 5.06e-32: 109: 51.11		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		661206 S10A2_HUMAN (1-90): 1.74e-31: 107: 52.22		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689700 S10A3_HUMAN (1-90): 4.12e-30: 104: 42.22		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		380746 S100B_HUMAN (3-93): 1.37e-29: 102: 58.24		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		416365 S10A9_HUMAN (3-92): 4.24e-29: 102: 37.36		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689703 S10AC_HUMAN (3-93): 7.31e-29: 101: 37.36		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		396691 S10A8_HUMAN (1-94): 1.35e-27: 97.6: 36.17		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		416580 S10A6_HUMAN (1-88): 1.92e-26: 94.5: 44.32		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689699 S10A5_HUMAN (1-94): 8.03e-25: 90.6: 45.75		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689708 S10AD_HUMAN (3-84): 2.15e-21: 82.2: 40.24		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689706 S1A7A_HUMAN (3-91): 7.74e-20: 78.3: 21.98		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689709 S10AE_HUMAN (3-84): 7.93e-20: 78.3: 26.83		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		666669 S100G_HUMAN (5-84): 5.27e-19: 75.6: 41.25		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		678415 S10A7_HUMAN (3-91): 9.61e-19: 75.6: 19.78		NAC1_HUMAN (1-973): 0: 1131: 100.00