Protein: IL37
Interleukin-37 (IL-37) (FIL1 zeta) (IL-1X) (Interleukin-1 family member 7) (IL-1F7) (Interleukin-1 homolog 4) (IL-1H) (IL-1H4) (Interleukin-1 zeta) (IL-1 zeta) (Interleukin-1-related protein) (IL-1RP1)

Gene: IL37
Organism: Homo sapiens
Interactions: 37
UniProt ID: Q9NZH6

Gene Ontology (top 5):
GO:0005125 - cytokine activity
GO:0005149 - interleukin-1 receptor binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1453253

IL37
Interleukin-37

2

0

Small-scale

0.770

High

712897

CASP1
Caspase-1

1

6

Small-scale

0.710

High

885715

CASP4
Caspase-4

1

6

Small-scale

0.710

High

1096934

FADD
FAS-associated death domain protein

3

3

High-throughput

0.667

High

391666

FRIH
Ferritin heavy chain

2

1

High-throughput

0.628

High

1106471

IL18R
Interleukin-18 receptor 1

2

9

Small-scale

0.608

High

1309531

DAA19
Dynein axonemal assembly factor 19

2

0

High-throughput

0.602

High

353836

I18BP
Interleukin-18-binding protein

1

0

Small-scale

0.586

High

225709

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

0

High-throughput

0.580

High

1453254

IRPL1
Interleukin-1 receptor accessory protein-like 1

1

9

Small-scale

0.553

High

666921

CCNC
Cyclin-C

1

0

High-throughput

0.513

High

722819

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

1

0

High-throughput

0.513

High

1249543

AMTN
Amelotin

1

0

High-throughput

0.513

High

1392543

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.513

High

1453256

PHF8
Histone lysine demethylase PHF8

1

0

High-throughput

0.513

High

442497

GELS
Gelsolin

1

0

High-throughput

0.493

High

650458

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.493

High

702507

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.493

High

1453255

UBQL1
Ubiquilin-1

1

0

High-throughput

0.493

High

292759

RENR
Renin receptor

1

2

High-throughput

0.489

High

1290381

MOGT3
2-acylglycerol O-acyltransferase 3

1

1

High-throughput

0.489

High

1014641

SMAD3
Mothers against decapentaplegic homolog 3

1

1

Small-scale

0.479

High

1391477

P2Y11
P2Y purinoceptor 11

1

4

High-throughput

0.470

High

1380871

TRI63
E3 ubiquitin-protein ligase TRIM63

1

2

High-throughput

0.439

High

1419312

TRI55
Tripartite motif-containing protein 55

1

2

High-throughput

0.439

High

1178500

GSG1
Germ cell-specific gene 1 protein

3

0

High-throughput

0.345

High

350509

GPAN1
G patch domain and ankyrin repeat-containing protein 1

1

0

High-throughput

0.279

Low

1204681

BEX5
Protein BEX5

1

0

High-throughput

0.279

Low

1216489

AHDC1
Transcription factor Gibbin

1

0

High-throughput

0.279

Low

1322530

D106A
Beta-defensin 106

1

0

High-throughput

0.279

Low

1439403

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

0

High-throughput

0.279

Low

1447064

TSSP
Thymus-specific serine protease

1

0

High-throughput

0.279

Low

1230847

SL9A4
Sodium/hydrogen exchanger 4

1

0

High-throughput

0.269

Low

1133928

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.268

Low

1453257

Q9Y649
GW128

1

0

High-throughput

0.268

Low

213433

ZSC12
Zinc finger and SCAN domain-containing protein 12

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025