Interactor 1: COF1 (P23528)
Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform)
Gene: CFL1

Interactor 2: ROCK1 (Q13464)
Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)
Gene: ROCK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 10436159
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000281 - mitotic cytokinesis
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007266 - Rho protein signal transduction
GO:0030027 - lamellipodium
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 166
Hs

1 1354
+ Hs
+ Hs
+ Hs
+ Zm
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024