HitPredict

Interactor 1: RPB1 (P24928)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
Gene: POLR2A

Interactor 2: RPA2 (Q9H9Y6)
DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135)
Gene: POLR1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 24981860
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb1_1~RNA_pol_Rpb2_1, RNA_pol_Rpb1_1~RNA_pol_Rpb2_6, RNA_pol_Rpb1_1~RNA_pol_Rpb2_7, RNA_pol_Rpb1_2~RNA_pol_Rpb2_6, RNA_pol_Rpb1_2~RNA_pol_Rpb2_7, RNA_pol_Rpb1_3~RNA_pol_Rpb2_1, RNA_pol_Rpb1_3~RNA_pol_Rpb2_6, RNA_pol_Rpa2_4~RNA_pol_Rpb1_4, RNA_pol_Rpb1_4~RNA_pol_Rpb2_1, RNA_pol_Rpb1_4~RNA_pol_Rpb2_3, RNA_pol_Rpb1_4~RNA_pol_Rpb2_6, RNA_pol_Rpb1_5~RNA_pol_Rpb2_1, RNA_pol_Rpb1_5~RNA_pol_Rpb2_3, RNA_pol_Rpb1_5~RNA_pol_Rpb2_6, RNA_pol_Rpb1_5~RNA_pol_Rpb2_7
Common GO terms GO:0003677 - DNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005654 - nucleoplasm
GO:0005694 - chromosome
GO:0008270 - zinc ion binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1970
Hs

1 1135
+ Bt
+ Hs
+ Hs
+ Hs
+ Sp
+ Sc
+ Hs
+ Hs
+ Sc
+ Sc
+ Pf
+ Hv
+ Pf
+ Hv
+ Nv
+ Ec
+ Bs
+ Hv
+ Hv
+ Mp

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Last updated: 15 Jul 2024