Protein: LSM6
LSM complex subunit LSM6

Gene: LSM6
Organism: Saccharomyces cerevisiae S288C
Interactions: 100
UniProt ID: Q06406

Gene Ontology (top 5):
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000398 - mRNA splicing, via spliceosome
GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

864133

LSM1
LSM1-LSM7 complex subunit LSM1

12

20

Small-scale

0.980

High

945352

LSM3
LSM complex subunit LSM3

9

20

Small-scale

0.973

High

818057

LSM4
LSM complex subunit LSM4

7

8

Small-scale

0.972

High

818487

LSM5
LSM complex subunit LSM5

9

6

Small-scale

0.971

High

865284

LSM8
LSM2-LSM8 complex subunit LSM8

8

20

Small-scale

0.970

High

678744

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

9

1

Small-scale

0.970

High

795927

LSM2
LSM complex subunit LSM2

6

20

Small-scale

0.945

High

924558

LSM7
LSM complex subunit LSM7

5

20

Small-scale

0.928

High

892971

SART3
U4/U6 snRNA-associated-splicing factor PRP24

4

2

Small-scale

0.891

High

1042454

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

3

3

High-throughput

0.861

High

751792

PRP8
Pre-mRNA-splicing factor 8

3

2

Small-scale

0.855

High

1054382

SMD2
Small nuclear ribonucleoprotein Sm D2

2

6

High-throughput

0.806

High

847835

SMD3
Small nuclear ribonucleoprotein Sm D3

2

20

Small-scale

0.789

High

1054946

RU2A
U2 small nuclear ribonucleoprotein A'

2

5

Small-scale

0.754

High

744168

BRR2
Pre-mRNA-splicing helicase BRR2

6

8

Small-scale

0.722

High

780226

SN114
Pre-mRNA-splicing factor SNU114

1

3

High-throughput

0.691

High

645542

XRN1
5'-3' exoribonuclease 1

5

0

High-throughput

0.684

High

812124

DHH1
ATP-dependent RNA helicase DHH1

3

4

High-throughput

0.669

High

886355

PRP31
Pre-mRNA-processing factor 31

3

3

High-throughput

0.667

High

1054941

LSM6
LSM complex subunit LSM6

1

3

High-throughput

0.665

High

627870

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

2

6

High-throughput

0.621

High

817166

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

5

High-throughput

0.618

High

1054951

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

2

3

Small-scale

0.611

High

721665

RENT1
ATP-dependent helicase NAM7

2

1

Small-scale

0.586

High

625049

PRP6
Pre-mRNA-splicing factor 6

1

9

High-throughput

0.536

High

1047386

RSE1
Pre-mRNA-splicing factor RSE1

1

2

High-throughput

0.536

High

1054944

DIB1
Spliceosomal protein DIB1

1

2

High-throughput

0.536

High

679003

NOT1
General negative regulator of transcription subunit 1

1

0

High-throughput

0.518

High

628233

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

6

High-throughput

0.515

High

909505

HFM1
ATP-dependent DNA helicase MER3

1

6

High-throughput

0.508

High

1054953

DCP1
mRNA-decapping enzyme subunit 1

1

0

Small-scale

0.493

High

1042535

CWC21
Pre-mRNA-splicing factor CWC21

1

1

Small-scale

0.479

High

1054950

CLF1
Pre-mRNA-splicing factor CLF1

1

12

Small-scale

0.479

High

708257

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

743786

RML2
Large ribosomal subunit protein uL2m

1

0

High-throughput

0.458

High

745884

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

783953

RM07
Large ribosomal subunit protein uL5m

1

0

High-throughput

0.458

High

1046857

RM01
Large ribosomal subunit protein uL1m

1

0

High-throughput

0.458

High

1054942

MHR1
Large ribosomal subunit protein mL67

1

0

High-throughput

0.458

High

1054949

NMD4
Nonsense-mediated decay protein 4

1

0

Small-scale

0.458

High

525239

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

527751

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

531898

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.445

High

546381

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

739206

PRP19
Pre-mRNA-processing factor 19

1

6

Small-scale

0.445

High

811406

CAJ1
Protein CAJ1

1

1

High-throughput

0.445

High

1025182

SEN1
Helicase SEN1

1

2

Small-scale

0.445

High

747246

RM06
Large ribosomal subunit protein uL6m

1

1

High-throughput

0.437

High

812680

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

432708

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.426

High

486324

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

752765

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

688720

YUR1
Probable mannosyltransferase YUR1

1

0

High-throughput

0.265

Low

1050137

FMP42
Protein FMP42

1

0

High-throughput

0.265

Low

1054947

YL053
Putative uncharacterized protein YLR053C

1

0

High-throughput

0.265

Low

1054948

GNT1
Glucose N-acetyltransferase 1

1

0

High-throughput

0.265

Low

550697

SIR4
Regulatory protein SIR4

1

0

Small-scale

0.249

Low

554645

RM02
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.249

Low

569517

RM31
Large ribosomal subunit protein mL60

1

0

High-throughput

0.249

Low

580109

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.249

Low

628181

RM33
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.249

Low

647943

RM08
Large ribosomal subunit protein bL17m

1

0

High-throughput

0.249

Low

648009

RM20
Large ribosomal subunit protein mL58

1

0

High-throughput

0.249

Low

657470

RM25
Large ribosomal subunit protein mL59

1

0

High-throughput

0.249

Low

672565

RM32
Large ribosomal subunit protein bL32m

1

0

High-throughput

0.249

Low

678215

IMG1
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.249

Low

678619

IMG2
Large ribosomal subunit protein mL49

1

0

High-throughput

0.249

Low

725752

RM09
Large ribosomal subunit protein uL3m

1

0

High-throughput

0.249

Low

736306

RM41
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.249

Low

758022

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

0

High-throughput

0.249

Low

778241

RM38
Large ribosomal subunit protein uL14m

1

0

High-throughput

0.249

Low

783825

RM03
Large ribosomal subunit protein mL44

1

0

High-throughput

0.249

Low

784019

RM10
Large ribosomal subunit protein uL15m

1

0

High-throughput

0.249

Low

784071

RM11
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.249

Low

784138

RM15
Large ribosomal subunit protein mL57

1

0

High-throughput

0.249

Low

784190

RM24
Large ribosomal subunit protein bL28m

1

0

High-throughput

0.249

Low

784233

RM27
Large ribosomal subunit protein mL41

1

0

High-throughput

0.249

Low

784287

RM28
Large ribosomal subunit protein mL40

1

0

High-throughput

0.249

Low

784355

RM17
Large ribosomal subunit protein mL46

1

0

High-throughput

0.249

Low

784442

RM37
Large ribosomal subunit protein mL54

1

0

High-throughput

0.249

Low

784469

RM39
Large ribosomal subunit protein bL33m

1

0

High-throughput

0.249

Low

792644

RM16
Large ribosomal subunit protein uL16m

1

0

High-throughput

0.249

Low

828563

RN49
Large ribosomal subunit protein bL21m

1

0

High-throughput

0.249

Low

909797

RL4P
Large ribosomal subunit protein uL4m

1

0

High-throughput

0.249

Low

917831

MNP1
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.249

Low

918463

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

922937

RM50
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.249

Low

924223

RM19
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.249

Low

924297

RM22
Large ribosomal subunit protein uL22m

1

0

High-throughput

0.249

Low

925389

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

1035296

RM13
Large ribosomal subunit protein mL50

1

0

High-throughput

0.249

Low

1041440

ATP25
ATPase synthesis protein 25, mitochondrial

1

0

High-throughput

0.249

Low

1053549

RM51
Large ribosomal subunit protein mL43

1

0

High-throughput

0.249

Low

1054943

RM35
Large ribosomal subunit protein mL38

1

0

High-throughput

0.249

Low

1054945

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

1054952

RM23
Large ribosomal subunit protein uL13m

1

0

High-throughput

0.249

Low

554050

TCPA
T-complex protein 1 subunit alpha

1

0

High-throughput

0.232

Low

747590

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.232

Low

836908

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025