Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: SKP1 (P63208)
S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (p19A) (Organ of Corti protein 2) (OCP-2) (Organ of Corti protein II) (OCP-II) (RNA polymerase II elongation factor-like protein) (SIII) (Transcription elongation factor B polypeptide 1-like) (p19skp1)
Gene: SKP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.751

The method score is based on:

Property Details
Experiments 33961781, 25852190, 26496610, 36736316, 16979657, 9636170, 7553852, 23602568
Identification Methods affinity chromatography technology, x-ray crystallography, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 298
Hs

1 163
+ Hs
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024