HitPredict

Interactor 1: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Interactor 2: ERBIN (Q96RT1)
Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2)
Gene: ERBIN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.627

Property	Details
Experiments	20936779, 15123239
Identification Methods	two hybrid, unspecified method, peptide array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0005912 - adherens junction GO:0007155 - cell adhesion
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2843 Hs			1 1412
+	Mm
		1193533 Q8BNP7_MOUSE (1-1058): 0: 1478: 95.09		SCRIB_MOUSE (219-1406): 4.49e-72: 268: 15.44
+	Hs
		626127 APC_HUMAN (1-2843): 0: 1316: 100.00		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		654037 MAP4_HUMAN (2119-2724): 1.19e-29: 131: 15.90		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		1050035 CIC_HUMAN (722-2643): 2.1e-17: 92.4: 7.79		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		1023220 CIC_HUMAN (722-2643): 2.1e-17: 92.4: 7.79		FLII_HUMAN (94-449): 1.19e-20: 101: 28.27