HitPredict

Interactor 1: MCM3 (P25206)
DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3)
Gene: MCM3

Interactor 2: EED (Q921E6)
Polycomb protein EED
Gene: EED

Species: Mus musculus

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 812 Mm			1 441
+	Hs
		627324 MCM3_HUMAN (1-812): 0: 930: 92.64		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Mm
		956196 MCM2_MOUSE (1-726): 0: 723: 29.42		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Mm
		956208 MCM6_MOUSE (2-778): 0: 669: 26.92		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Mm
		831953 MCM4_MOUSE (9-745): 0: 662: 28.20		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		832625 MCM2_HUMAN (1-726): 0: 720: 29.56		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		1055604 MCM6_HUMAN (2-778): 0: 659: 26.56		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		709001 MCM7_HUMAN (10-713): 0: 657: 29.97		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		708496 MCM4_HUMAN (9-745): 0: 659: 27.81		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		709008 MCM7_HUMAN (10-713): 0: 657: 29.97		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		708826 MCM7_HUMAN (10-713): 0: 657: 29.97		LIS1_HUMAN (332-438): 2.37e-14: 76.5: 18.69
+	Hs
		708541 MCM4_HUMAN (9-745): 0: 659: 27.81		FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97
+	Mm
		1143181 MCM7_MOUSE (98-674): 2.83e-84: 285: 36.64		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Sc
		667875 MCM5_YEAST (8-650): 6.35e-87: 293: 30.89		COPA_YEAST (15-182): 2.3e-11: 68.1: 10.71