Interactor 1: ACM3 (P20309)
Muscarinic acetylcholine receptor M3
Gene: CHRM3
Interactor 2: GNAS2 (P63092)
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (EC 3.6.5.-) (Adenylate cyclase-stimulating G alpha protein)
Gene: GNAS
Species: Homo sapiens
Source: mint
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.48 | 1.00 | 0.698 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28298427 |
| Identification Methods | two hybrid, ubiquitin reconstruction |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 7tm_1~G-alpha |
| Common GO terms | GO:0005886 - plasma membrane GO:0007186 - G protein-coupled receptor signaling pathway |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025