HitPredict

Interactor 1: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Interactor 2: LMTK2 (Q8IWU2)
Serine/threonine-protein kinase LMTK2 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase 2) (Brain-enriched kinase) (hBREK) (CDK5/p35-regulated kinase) (CPRK) (Kinase/phosphatase/inhibitor 2) (Lemur tyrosine kinase 2) (Serine/threonine-protein kinase KPI-2)
Gene: LMTK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~Ras
Common GO terms	GO:0048471 - perinuclear region of cytoplasm GO:0055037 - recycling endosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 218 Hs			1 1503
+	Hs
		976396 RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33		LMTK2_HUMAN (1-1503): 0: 1229: 100.00
+	Hs
		710801 RAB2A_HUMAN (10-197): 4.01e-95: 278: 56.92		EPHB2_HUMAN (47-480): 1.21e-119: 403: 22.10
+	Hs
		317283 RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33		STK10_HUMAN (120-983): 2.03e-126: 420: 17.67
+	Hs
		710153 RAB2A_HUMAN (10-197): 4.01e-95: 278: 56.92		EPHA2_HUMAN (81-437): 3.66e-109: 372: 24.31
+	Hs
		541331 RAB4A_HUMAN (1-218): 3.71e-86: 255: 100.00		FGFR1_HUMAN (36-471): 4.94e-118: 393: 21.41
+	Hs
		541423 RAB1A_HUMAN (3-218): 1.74e-85: 253: 38.43		FGFR1_HUMAN (36-471): 4.94e-118: 393: 21.41
+	Hs
		541422 RAB14_HUMAN (3-217): 2.22e-83: 248: 57.21		FGFR1_HUMAN (36-471): 4.94e-118: 393: 21.41
+	Hs
		710697 RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33		EPHA8_HUMAN (22-410): 1.08e-116: 394: 24.24
+	Hs
		541510 RB11B_HUMAN (3-217): 4.38e-83: 247: 43.26		FGFR1_HUMAN (36-471): 4.94e-118: 393: 21.41
+	Hs
		541613 RAB2B_HUMAN (10-218): 1.43e-81: 244: 51.87		FGFR1_HUMAN (36-471): 4.94e-118: 393: 21.41
+	Hs
		463431 RAB2A_HUMAN (10-197): 4.01e-95: 278: 56.92		LYN_HUMAN (86-421): 3.37e-109: 358: 22.19
+	Hs
		630695 RAB4A_HUMAN (1-218): 3.71e-86: 255: 100.00		EPHA2_HUMAN (81-437): 3.66e-109: 372: 24.31
+	Hs
		710160 RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33		EPHA2_HUMAN (81-437): 3.66e-109: 372: 24.31
+	Hs
		411698 RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33		NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33
+	Hs
		439696 RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33		INSR_HUMAN (93-407): 2.86e-34: 145: 32.82
+	Hs
		465472 RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33		IGF1R_HUMAN (131-399): 1.23e-33: 144: 33.33
+	Rn
		72606 B0BMW0_RAT (3-217): 2.22e-83: 248: 57.21		INSR_RAT (131-407): 3.24e-32: 139: 33.57
+	Rn
		204896 RB11B_RAT (3-217): 4.38e-83: 247: 43.26		INSR_RAT (131-407): 3.24e-32: 139: 33.57
+	Rn
		580463 RB11A_RAT (3-217): 3.63e-83: 247: 42.33		INSR_RAT (131-407): 3.24e-32: 139: 33.57
+	Rn
		108121 G3V6H0_RAT (6-218): 3.7e-82: 244: 39.44		INSR_RAT (131-407): 3.24e-32: 139: 33.57