Interactor 1: SPB1 (P25582)
27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase (EC 2.1.1.167) (2'-O-ribose RNA methyltransferase SPB1) (AdoMet-dependent rRNA methyltransferase SPB1) (S-adenosyl-L-methionine-dependent methyltransferase) (Suppressor of PAB1 protein 1)
Gene: SPB1

Interactor 2: NUG1 (P40010)
Nuclear GTP-binding protein NUG1 (Nuclear GTPase 1)
Gene: NUG1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.728

The method score is based on:

Property Details
Experiments 11583615, 12374754, 26823502, 36929751, 37968396, 38113283
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0030687 - preribosome, large subunit precursor
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 841
Sc

1 520
+ Sc
+ Dm
+ Dm
+ Hs
+ Sc
+ Sc

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Last updated: 15 Jul 2024