HitPredict

Interactor 1: PWP2 (P25635)
Periodic tryptophan protein 2 (U three protein 1) (U3 small nucleolar RNA-associated protein 1) (U3 snoRNA-associated protein 1)
Gene: PWP2

Interactor 2: PNO1 (Q99216)
Pre-rRNA-processing protein PNO1 (Partner of NOB1) (Ribosomal RNA-processing protein 20)
Gene: PNO1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.697

Property	Details
Experiments	29263326, 16429126, 35650250, 37968396
Identification Methods	two hybrid, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0030686 - 90S preribosome
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 923 Sc			1 274
+	Sc
		1015339 UTP12_YEAST (1-122): 1.57e-21: 103: 15.20		PNO1_YEAST (1-274): 2.78e-152: 427: 100.00