Interactor 1: TNR5 (P25942)
Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CDw40) (CD antigen CD40)
Gene: CD40

Interactor 2: TN13B (Q9Y275)
Tumor necrosis factor ligand superfamily member 13B (B lymphocyte stimulator) (BLyS) (B-cell-activating factor) (BAFF) (Dendritic cell-derived TNF-like molecule) (TNF- and APOL-related leukocyte expressed ligand 1) (TALL-1) (CD antigen CD257) [Cleaved into: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form]
Gene: TNFSF13B

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 17567982, 16644731
Identification Methods anti tag coimmunoprecipitation, electrophoretic mobility supershift assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TNF~TNFR_c6
Common GO terms GO:0005886 - plasma membrane
GO:0030890 - positive regulation of B cell proliferation
GO:0042100 - B cell proliferation
GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 277
Hs

1 285
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024