HitPredict

Interactor 1: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Interactor 2: IF4A1 (P60842)
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)
Gene: EIF4A1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26641092
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 475 Hs			1 406
+	Hs
		571317 U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00		DDX5_HUMAN (10-406): 3.38e-138: 409: 29.88
+	Hs
		641875 U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00		DDX17_HUMAN (2-406): 1.31e-136: 409: 29.33
+	Hs
		641649 U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00		IF4A3_HUMAN (1-406): 1.93e-134: 393: 66.75
+	Zm
		20961 B4FWC4_MAIZE (10-469): 1.43e-45: 168: 18.74		A0A1D6HQ89_MAIZE (1-406): 0: 515: 57.88
+	Hs
		1077436 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		DDX17_HUMAN (2-406): 1.31e-136: 409: 29.33
+	Hs
		571469 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		DDX5_HUMAN (10-406): 3.38e-138: 409: 29.88
+	Hs
		1054481 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		DDX17_HUMAN (2-406): 1.31e-136: 409: 29.33
+	Hs
		571452 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		DDX5_HUMAN (10-406): 3.38e-138: 409: 29.88
+	Hs
		757611 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		IF4A3_HUMAN (1-406): 1.93e-134: 393: 66.75
+	Hs
		892803 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		IF4A1_HUMAN (1-406): 1.84e-132: 387: 100.00
+	Mm
		857323 TIA1_MOUSE (253-475): 4.2e-36: 139: 15.70		DDX17_MOUSE (2-406): 1.38e-137: 409: 29.33
+	Mm
		857351 TIA1_MOUSE (253-475): 4.2e-36: 139: 15.70		Q8BTS0_MOUSE (10-406): 4.82e-138: 409: 29.88
+	Hs
		1031325 PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78		IF4A2_HUMAN (4-406): 4.47e-158: 453: 90.32
+	Mm
		857295 TIA1_MOUSE (253-475): 4.2e-36: 139: 15.70		IF4A1_MOUSE (1-406): 1.84e-132: 387: 100.00
+	Hs
		640489 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		DDX6_HUMAN (32-402): 1.66e-88: 278: 38.71
+	Hs
		516391 PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35		IF4A3_HUMAN (1-406): 1.93e-134: 393: 66.75
+	Hs
		892791 PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78		IF4A1_HUMAN (1-406): 1.84e-132: 387: 100.00
+	Hs
		640477 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		DDX6_HUMAN (32-402): 1.66e-88: 278: 38.71
+	Hs
		640464 PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78		DDX6_HUMAN (32-402): 1.66e-88: 278: 38.71
+	Hs
		516363 PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35		DDX6_HUMAN (32-402): 1.66e-88: 278: 38.71