HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: PTN4 (P29074)
Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1)
Gene: PTPN4

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	27880917, 27432908, 28330616, 28675297
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 926
+	Hs
		663970 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PTN4_HUMAN (1-926): 0: 949: 100.00
+	Hs
		640229 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PTN3_HUMAN (1-923): 0: 817: 50.53
+	Hs
		640212 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PTN3_HUMAN (1-923): 0: 817: 50.53
+	Hs
		640230 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		PTN3_HUMAN (1-923): 0: 817: 50.53
+	Hs
		910025 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		E41L1_HUMAN (12-647): 6.92e-145: 453: 27.85
+	Hs
		647274 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		E41L1_HUMAN (12-647): 6.92e-145: 453: 27.85
+	Hs
		910185 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		E41L3_HUMAN (21-682): 1.53e-132: 427: 27.22
+	Hs
		505612 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		EPB41_HUMAN (8-562): 2.24e-133: 423: 30.21
+	Hs
		204644 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		E41L2_HUMAN (17-665): 1.48e-130: 419: 28.12
+	Hs
		647400 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		E41L3_HUMAN (21-682): 1.53e-132: 427: 27.22
+	Hs
		647300 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		E41L5_HUMAN (1-600): 4.34e-136: 426: 26.36
+	Hs
		505557 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		EPB41_HUMAN (8-562): 2.24e-133: 423: 30.21
+	Hs
		204614 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		E41L2_HUMAN (17-665): 1.48e-130: 419: 28.12
+	Hs
		204648 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		E41L2_HUMAN (17-665): 1.48e-130: 419: 28.12
+	Hs
		647056 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		FRMD5_HUMAN (1-508): 4.92e-129: 402: 27.47
+	Hs
		909498 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PTN13_HUMAN (618-912): 9.57e-104: 357: 35.02
+	Hs
		646848 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PTN13_HUMAN (618-912): 9.57e-104: 357: 35.02
+	Hs
		577010 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		PTPRA_HUMAN (639-912): 7.66e-96: 321: 33.45
+	Hs
		909595 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PTN14_HUMAN (30-319): 6.01e-30: 130: 31.00
+	Hs
		646918 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PTN14_HUMAN (30-319): 6.01e-30: 130: 31.00