HitPredict

Interactor 1: CALL3 (P27482)
Calmodulin-like protein 3 (CaM-like protein) (CLP) (Calmodulin-related protein NB-1)
Gene: CALML3

Interactor 2: KCC2G (Q13555)
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)
Gene: CAMK2G

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF-hand_7~Pkinase
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 149 Hs			1 558
+	Hs
		483927 CALM1_HUMAN (1-149): 1.19e-56: 175: 84.56		KCC2G_HUMAN (1-558): 0: 672: 100.00
+	Hs
		484001 CALM2_HUMAN (1-149): 1.19e-56: 175: 84.56		KCC2G_HUMAN (1-558): 0: 672: 100.00
+	Hs
		484119 CALM3_HUMAN (1-149): 1.19e-56: 175: 84.56		KCC2G_HUMAN (1-558): 0: 672: 100.00
+	Dm
		906661 CALM_DROME (1-149): 2.47e-56: 174: 85.91		KCC2A_DROME (1-552): 0: 574: 67.94
+	Dm
		825619 CALL_DROME (3-149): 1.37e-55: 172: 62.59		KCC2A_DROME (1-552): 0: 574: 67.94
+	Hs
		483928 CALM1_HUMAN (1-149): 1.19e-56: 175: 84.56		KCC2D_HUMAN (1-558): 0: 525: 64.88
+	Hs
		484002 CALM2_HUMAN (1-149): 1.19e-56: 175: 84.56		KCC2D_HUMAN (1-558): 0: 525: 64.88
+	Hs
		484120 CALM3_HUMAN (1-149): 1.19e-56: 175: 84.56		KCC2D_HUMAN (1-558): 0: 525: 64.88
+	Hs
		483929 CALM1_HUMAN (1-149): 1.19e-56: 175: 84.56		KCC1A_HUMAN (6-336): 4.19e-138: 406: 37.76
+	Hs
		483947 CALM1_HUMAN (1-149): 1.19e-56: 175: 84.56		KCC1D_HUMAN (2-315): 8.38e-138: 406: 38.80
+	Ce
		183804 CALM_CAEEL (1-149): 3.07e-56: 174: 85.24		CMK1_CAEEL (2-339): 7.85e-138: 405: 38.05
+	At
		483086 CALM4_ARATH (1-149): 8.98e-54: 168: 80.54		CDPK3_ARATH (14-332): 9.72e-137: 408: 32.71
+	At
		886549 CALM7_ARATH (1-149): 1.05e-53: 168: 81.88		CDPK3_ARATH (14-332): 9.72e-137: 408: 32.71
+	Hs
		648500 CALL3_HUMAN (1-149): 2.03e-54: 169: 100.00		KCC1A_HUMAN (6-336): 4.19e-138: 406: 37.76
+	Hs
		648542 CALL3_HUMAN (1-149): 2.03e-54: 169: 100.00		KCC1D_HUMAN (2-315): 8.38e-138: 406: 38.80
+	At
		976625 CALM6_ARATH (1-149): 1.36e-53: 167: 82.55		CDPK3_ARATH (14-332): 9.72e-137: 408: 32.71
+	Dm
		906677 CALM_DROME (1-149): 2.47e-56: 174: 85.91		Q7JMV3_DROME (12-312): 4.09e-70: 232: 41.51
+	Hs
		483926 CALM1_HUMAN (1-149): 1.19e-56: 175: 84.56		KCC2B_HUMAN (287-558): 1.59e-57: 205: 49.29
+	Hs
		484000 CALM2_HUMAN (1-149): 1.19e-56: 175: 84.56		KCC2B_HUMAN (287-558): 1.59e-57: 205: 49.29
+	Hs
		484118 CALM3_HUMAN (1-149): 1.19e-56: 175: 84.56		KCC2B_HUMAN (287-558): 1.59e-57: 205: 49.29