HitPredict

Interactor 1: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 806 Hs			1 618
+	Hs
		710616 EPHA3_HUMAN (1-786): 0: 641: 20.68		RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22
+	Hs
		710629 EPHA3_HUMAN (1-786): 0: 641: 20.68		RAB35_HUMAN (5-168): 3.57e-76: 242: 24.70
+	Hs
		581065 EPHA7_HUMAN (1-782): 0: 623: 21.22		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		580953 EPHA5_HUMAN (1-777): 0: 621: 20.18		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		953464 EPHA7_HUMAN (1-782): 0: 623: 21.22		RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22
+	Hs
		710836 EPHB2_HUMAN (6-788): 0: 629: 19.23		RAB35_HUMAN (5-168): 3.57e-76: 242: 24.70
+	Hs
		931827 EPHA5_HUMAN (1-777): 0: 621: 20.18		RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22
+	Hs
		1144913 EPHA7_HUMAN (1-782): 0: 623: 21.22		RAB35_HUMAN (5-168): 3.57e-76: 242: 24.70
+	Hs
		931828 EPHA5_HUMAN (1-777): 0: 621: 20.18		CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54
+	Hs
		1015454 EPHA7_HUMAN (1-782): 0: 623: 21.22		RHOG_HUMAN (3-170): 1.69e-74: 238: 27.47
+	Hs
		988385 EPHA7_HUMAN (1-782): 0: 623: 21.22		RAC1_HUMAN (3-181): 3.96e-74: 237: 26.43
+	Hs
		931832 EPHA5_HUMAN (1-777): 0: 621: 20.18		RAC1_HUMAN (3-181): 3.96e-74: 237: 26.43
+	Hs
		710804 EPHB2_HUMAN (6-788): 0: 629: 19.23		RHOB_HUMAN (6-168): 4.59e-13: 70.1: 29.38
+	Hs
		978024 EPHA7_HUMAN (1-782): 0: 623: 21.22		RHOB_HUMAN (6-168): 4.59e-13: 70.1: 29.38
+	Hs
		931829 EPHA5_HUMAN (1-777): 0: 621: 20.18		RHOB_HUMAN (6-168): 4.59e-13: 70.1: 29.38
+	Hs
		962074 EPHA7_HUMAN (1-782): 0: 623: 21.22		RHOA_HUMAN (6-168): 1.75e-11: 65.5: 28.25
+	Hs
		466267 EPHA7_HUMAN (1-782): 0: 623: 21.22		RHOC_HUMAN (6-168): 3.88e-11: 64.3: 28.25
+	Hs
		601301 EPHA7_HUMAN (1-782): 0: 623: 21.22		RHOQ_HUMAN (5-169): 2.03e-10: 62.8: 26.26
+	Hs
		466171 EPHA5_HUMAN (1-777): 0: 621: 20.18		RHOC_HUMAN (6-168): 3.88e-11: 64.3: 28.25
+	Hs
		126522 EPHA5_HUMAN (1-777): 0: 621: 20.18		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89