HitPredict

Interactor 1: GRN (P28799)
Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)]
Gene: GRN

Interactor 2: KLF3 (P57682)
Krueppel-like factor 3 (Basic krueppel-like factor) (CACCC-box-binding protein BKLF) (TEF-2)
Gene: KLF3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.549

Property	Details
Experiments	35140242, 32814053
Identification Methods	proximity labelling technology, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 593 Hs			1 345
+	Hs
		660751 GRN_HUMAN (1-593): 0: 726: 100.00		ZN180_HUMAN (94-344): 5.12e-60: 206: 16.18
+	Hs
		660747 GRN_HUMAN (1-593): 0: 726: 100.00		KLF15_HUMAN (258-342): 8.09e-30: 119: 63.53
+	Hs
		660506 GRN_HUMAN (1-593): 0: 726: 100.00		ZKSC8_HUMAN (285-345): 1.75e-19: 91.3: 42.62