HitPredict

Interactor 1: GATA2 (P23769)
Endothelial transcription factor GATA-2 (GATA-binding protein 2)
Gene: GATA2

Interactor 2: RCOR3 (Q9P2K3)
REST corepressor 3
Gene: RCOR3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 480 Hs			1 495
+	Hs
		662515 GATA2_HUMAN (1-480): 0: 529: 100.00		RCOR1_HUMAN (1-384): 4.08e-96: 300: 63.47
+	Hs
		662665 GATA3_HUMAN (1-480): 3.12e-135: 399: 61.24		RCOR3_HUMAN (1-495): 5.58e-139: 411: 100.00
+	Hs
		278238 GATA2_HUMAN (1-480): 0: 529: 100.00		NCOR1_HUMAN (35-484): 3.12e-50: 187: 17.04
+	Hs
		662672 GATA3_HUMAN (1-480): 3.12e-135: 399: 61.24		RCOR1_HUMAN (1-384): 4.08e-96: 300: 63.47
+	Hs
		662526 GATA2_HUMAN (1-480): 0: 529: 100.00		NCOR2_HUMAN (35-478): 2.11e-43: 166: 18.02
+	Hs
		662644 GATA3_HUMAN (1-480): 3.12e-135: 399: 61.24		MTA3_HUMAN (1-422): 3.15e-89: 286: 16.16
+	Hs
		590506 GATA1_HUMAN (186-480): 8.36e-69: 227: 43.35		RCOR3_HUMAN (1-495): 5.58e-139: 411: 100.00
+	Hs
		278239 GATA3_HUMAN (1-480): 3.12e-135: 399: 61.24		NCOR1_HUMAN (35-484): 3.12e-50: 187: 17.04
+	Hs
		662679 GATA3_HUMAN (1-480): 3.12e-135: 399: 61.24		NCOR2_HUMAN (35-478): 2.11e-43: 166: 18.02
+	Hs
		316775 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		MTA2_HUMAN (1-478): 2.97e-92: 296: 15.71
+	Mm
		607343 GATA1_MOUSE (103-479): 1.91e-68: 226: 35.77		MTA2_MOUSE (1-478): 4.26e-93: 298: 15.53
+	Hs
		851655 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		MTA3_HUMAN (1-422): 3.15e-89: 286: 16.16
+	Hs
		1459933 TRPS1_HUMAN (153-447): 1.97e-56: 204: 23.76		RCOR1_HUMAN (1-384): 4.08e-96: 300: 63.47
+	Hs
		317027 TRPS1_HUMAN (153-447): 1.97e-56: 204: 23.76		MTA2_HUMAN (1-478): 2.97e-92: 296: 15.71
+	Hs
		1413360 TRPS1_HUMAN (153-447): 1.97e-56: 204: 23.76		MTA3_HUMAN (1-422): 3.15e-89: 286: 16.16
+	Hs
		851549 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		MTA1_HUMAN (1-401): 2.88e-75: 252: 16.04
+	Hs
		1102681 TRPS1_HUMAN (153-447): 1.97e-56: 204: 23.76		MTA1_HUMAN (1-401): 2.88e-75: 252: 16.04
+	Hs
		278267 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		NCOR1_HUMAN (35-484): 3.12e-50: 187: 17.04
+	Hs
		851716 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		NCOR2_HUMAN (35-478): 2.11e-43: 166: 18.02
+	Hs
		590512 GATA1_HUMAN (186-480): 8.36e-69: 227: 43.35		NCOR2_HUMAN (35-478): 2.11e-43: 166: 18.02