Interactor 1: CCND1 (P24385)
G1/S-specific cyclin-D1 (B-cell lymphoma 1 protein) (BCL-1) (BCL-1 oncogene) (PRAD1 oncogene)
Gene: CCND1

Interactor 2: CDN1B (P46527)
Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1)
Gene: CDKN1B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 11360184, 33854239, 34591612, 9311993, 11940657, 25416956, 26496610, 19767775, 28514442, 21654808, 16431923, 33961781, 15695403, 8978686, 19556892, 12036906, 17053782, 17254966, 34591642, 9106657 and 1 others

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Identification Methods pull down, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDI~Cyclin_N
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 2 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 295
Hs

1 198
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Service provided by Combinatics, Japan

Last updated: 11Aug2025