HitPredict

Interactor 1: CCND1 (P24385)
G1/S-specific cyclin-D1 (B-cell lymphoma 1 protein) (BCL-1) (BCL-1 oncogene) (PRAD1 oncogene)
Gene: CCND1

Interactor 2: CDN1C (P49918)
Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57Kip2)
Gene: CDKN1C

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.948

The method score is based on:

Property Details
Experiments 10713702, 10764802, 28514442, 33961781, 34591642, unassigned3799
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDI~Cyclin_N
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0044877 - protein-containing complex binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 295
Hs

1 316
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Xl
+ Xl

Service provided by Combinatics, Japan

Last updated: 11Aug2025