HitPredict

Interactor 1: PTN6 (P29350)
Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Protein-tyrosine phosphatase SHP-1) (SH-PTP1)
Gene: PTPN6

Interactor 2: FCG2B (P31994)
Low affinity immunoglobulin gamma Fc region receptor II-b (IgG Fc receptor II-b) (CDw32) (Fc-gamma RII-b) (Fc-gamma-RIIb) (FcRII-b) (CD antigen CD32)
Gene: FCGR2B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.656

The method score is based on:

Property Details
Experiments 8577729, 9148918, 9603468
Identification Methods pull down, proteinchip(r) on a surface-enhanced laser desorption/ionization, affinity chromatography technology
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002924 - negative regulation of humoral immune response mediated by circulating immunoglobulin
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 595
Hs

1 310
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024