Interactor 1: IL12B (P29460)
Interleukin-12 subunit beta (IL-12B) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (IL-12 subunit p40) (NK cell stimulatory factor chain 2) (NKSF2)
Gene: IL12B
Interactor 2: I12R1 (P42701)
Interleukin-12 receptor subunit beta-1 (IL-12 receptor subunit beta-1) (IL-12R subunit beta-1) (IL-12R-beta-1) (IL-12RB1) (IL-12 receptor beta component) (CD antigen CD212)
Gene: IL12RB1
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.56 | 1.00 | 0.754 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | IL12p40_C~fn3 |
Common GO terms | GO:0001916 - positive regulation of T cell mediated cytotoxicity GO:0002230 - positive regulation of defense response to virus by host GO:0002827 - positive regulation of T-helper 1 type immune response GO:0004896 - cytokine receptor activity GO:0009897 - external side of plasma membrane and 10 others more... |
Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024