Interactor 1: TRXB1 (P29509)
Thioredoxin reductase 1 (TR) (TrxR) (EC 1.8.1.9) (Thioredoxin peroxidase 1) (TPx) (Thioredoxin-dependent peroxide reductase 1)
Gene: TRR1

Interactor 2: TRXB2 (P38816)
Thioredoxin reductase 2, mitochondrial (EC 1.8.1.9)
Gene: TRR2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.955

The method score is based on:

Property Details
Experiments 16554755, 37968396, 20826334, 18719252, 22940862, unassigned1933, 16429126
Identification Methods affinity chromatography technology, two hybrid, dihydrofolate reductase reconstruction, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pyr_redox_2~Pyr_redox_2
Common GO terms GO:0004791 - thioredoxin-disulfide reductase (NADPH) activity
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0019430 - removal of superoxide radicals
GO:0034599 - cellular response to oxidative stress
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 319
Sc

1 342
+ Sc
+ Sc
+ At
+ Os
+ Sp
+ Cj
+ Dm
+ Dm
+ Ec
+ Zm
+ Hs
+ Ec
+ Rn
+ Ec
+ Mp

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Last updated: 15 Jul 2024