HitPredict

Interactor 1: PML (P29590)
Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19)
Gene: PML

Interactor 2: FHL3 (Q13643)
Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM-protein 2) (SLIM-2)
Gene: FHL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 882 Hs			1 280
+	Hs
		668516 PML_HUMAN (1-882): 0: 902: 100.00		PAXI_HUMAN (3-218): 4.3e-73: 236: 28.70
+	Hs
		668514 PML_HUMAN (1-882): 0: 902: 100.00		LIMS1_HUMAN (37-278): 1.46e-46: 160: 23.48
+	Hs
		668885 PML_HUMAN (1-882): 0: 902: 100.00		LPP_HUMAN (3-153): 3.55e-38: 143: 29.38
+	Hs
		150526 PML_HUMAN (1-882): 0: 902: 100.00		ABLM1_HUMAN (3-147): 6.59e-28: 114: 24.03
+	Hs
		668677 PML_HUMAN (1-882): 0: 902: 100.00		FHL2_HUMAN (4-156): 1.41e-24: 101: 26.45
+	Hs
		1044739 TRI33_HUMAN (56-558): 4.27e-74: 265: 15.56		FHL3_HUMAN (1-280): 8.02e-79: 241: 100.00
+	Hs
		1029400 TIF1B_HUMAN (7-593): 6.89e-69: 247: 13.97		FHL3_HUMAN (1-280): 8.02e-79: 241: 100.00
+	Mm
		1307943 TRIM8_MOUSE (51-538): 1.5e-69: 242: 14.61		FHL3_MOUSE (1-280): 1.6e-74: 230: 94.46
+	Hs
		816239 TIF1B_HUMAN (7-593): 6.89e-69: 247: 13.97		LIMS1_HUMAN (37-278): 1.46e-46: 160: 23.48
+	Hs
		1293398 TRI39_HUMAN (48-434): 3.1e-57: 207: 11.37		PDLI5_HUMAN (3-155): 6.13e-48: 169: 28.76
+	Hs
		175706 TRI18_HUMAN (48-411): 5.87e-56: 207: 14.22		PDLI5_HUMAN (3-155): 6.13e-48: 169: 28.76
+	Hs
		1052735 TRI25_HUMAN (42-366): 2.13e-54: 201: 16.67		PDLI5_HUMAN (3-155): 6.13e-48: 169: 28.76
+	Hs
		1293392 TRI56_HUMAN (34-536): 3.5e-53: 200: 18.41		PDLI5_HUMAN (3-155): 6.13e-48: 169: 28.76
+	Hs
		584958 RO52_HUMAN (44-414): 8.03e-56: 202: 13.46		FHL1_HUMAN (66-279): 2.38e-43: 151: 29.17
+	Hs
		1029412 TIF1B_HUMAN (7-593): 6.89e-69: 247: 13.97		FHL2_HUMAN (4-156): 1.41e-24: 101: 26.45