Interactor 1: PML (P29590)
Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19)
Gene: PML

Interactor 2: KLH20 (Q9Y2M5)
Kelch-like protein 20 (Kelch-like ECT2-interacting protein) (Kelch-like protein X)
Gene: KLHL20

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.60 0.715

The method score is based on:

Property Details
Experiments 25619834, 24487962, 20389280, 21840486
Identification Methods affinity chromatography technology, pull down, enzymatic study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, competition binding
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016605 - PML body
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 882
Hs

1 609
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024