HitPredict

Interactor 1: CLH (P29742)
Clathrin heavy chain
Gene: Chc

Interactor 2: Q9W329 (Q9W329)
Golgi-localized, gamma-adaptin ear containing, ARF binding protein (Golgi-localizing gamma-ear-containing ARF-binding protein) (LD41311p)
Gene: Gga

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20067992
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Alpha_adaptinC2~Clathrin
Common GO terms	GO:0005802 - trans-Golgi network GO:0006886 - intracellular protein transport GO:0030136 - clathrin-coated vesicle GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1678 Dm			1 660
+	Hs
		961013 CLH1_HUMAN (1-1660): 0: 2995: 80.17		GGA1_HUMAN (5-643): 1.26e-115: 362: 23.33
+	Hs
		960999 CLH1_HUMAN (1-1660): 0: 2995: 80.17		GGA3_HUMAN (1-643): 3.53e-113: 358: 21.64
+	Hs
		961012 CLH1_HUMAN (1-1660): 0: 2995: 80.17		GGA2_HUMAN (5-644): 1.58e-103: 329: 20.46
+	Hs
		960857 CLH1_HUMAN (1-1660): 0: 2995: 80.17		TM1L2_HUMAN (5-497): 4.06e-95: 304: 14.51
+	Hs
		241163 CLH1_HUMAN (1-1660): 0: 2995: 80.17		TOM1_HUMAN (5-486): 2.68e-90: 291: 16.80
+	Mm
		1148410 CLH1_MOUSE (1-1660): 0: 2994: 80.23		TM1L1_MOUSE (5-475): 6.15e-71: 239: 16.18
+	Hs
		272801 CLH1_HUMAN (1-1660): 0: 2995: 80.17		TM1L1_HUMAN (5-455): 2.24e-70: 238: 15.37
+	Hs
		960908 CLH1_HUMAN (1-1660): 0: 2995: 80.17		STAM1_HUMAN (4-524): 1.34e-68: 235: 13.16
+	Hs
		159961 CLH1_HUMAN (1-1660): 0: 2995: 80.17		HGS_HUMAN (1-615): 2.05e-60: 217: 10.15
+	Mm
		1148412 CLH1_MOUSE (1-1660): 0: 2994: 80.23		HGS_MOUSE (1-616): 9.67e-59: 213: 10.60
+	Hs
		212619 CLH1_HUMAN (1-1660): 0: 2995: 80.17		AP1G1_HUMAN (430-639): 8.25e-53: 196: 17.34
+	Dm
		669603 CLH_DROME (1-1678): 0: 2944: 100.00		HRS_DROME (6-620): 2.82e-63: 225: 11.57
+	Hs
		241158 CLH2_HUMAN (1-1634): 0: 2827: 77.11		TOM1_HUMAN (5-486): 2.68e-90: 291: 16.80
+	Hs
		863981 CLH2_HUMAN (1-1634): 0: 2827: 77.11		STAM1_HUMAN (4-524): 1.34e-68: 235: 13.16
+	Ce
		712329 CLH_CAEEL (5-1659): 0: 2777: 70.66		Q17796_CAEEL (5-383): 9.18e-65: 229: 12.56
+	Zm
		25357 A0A1D6IQ85_MAIZE (6-1638): 0: 2663: 56.65		C4J1G1_MAIZE (13-562): 3.48e-65: 227: 15.93
+	Sc
		604476 CLH_YEAST (5-1652): 0: 2443: 48.70		GGA1_YEAST (3-421): 3.82e-63: 221: 19.33
+	Sc
		604424 CLH_YEAST (5-1652): 0: 2443: 48.70		VPS27_YEAST (3-597): 7.71e-58: 207: 9.92
+	Sc
		604404 CLH_YEAST (5-1652): 0: 2443: 48.70		GGA2_YEAST (252-642): 3.06e-14: 78.2: 12.32