HitPredict

Interactor 1: PSA2 (P25787)
Proteasome subunit alpha type-2 (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (Proteasome component C3) (Proteasome subunit alpha-2) (alpha-2)
Gene: PSMA2

Interactor 2: PSA5 (P28066)
Proteasome subunit alpha type-5 (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain) (Proteasome subunit alpha-5) (alpha-5) (Proteasome zeta chain)
Gene: PSMA5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.950

The method score is based on:

Property Details
Experiments 33961781, 35271311, 12376572, 19193609, 15887188, unassigned3799
Identification Methods affinity chromatography technology, biochemical, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Proteasome~Proteasome, Proteasome~Proteasome_A_N, Proteasome_A_N~Proteasome_A_N
Common GO terms GO:0000502 - proteasome complex
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 7 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 234
Hs

1 241
+ Hs
+ Dm
+ Hv
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ss
+ Hs
+ Hs
+ Sp
+ Ce
+ Sp
+ Zm
+ Hs
+ Hs
+ Ce
+ Ce

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Last updated: 11Aug2025