HitPredict

Interactor 1: DNJA1 (P31689)
DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)
Gene: DNAJA1

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	33306668, 16169070
Identification Methods	affinity chromatography technology, two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 397 Hs			1 496
+	Hs
		681549 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		243532 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		1309166 DNJB4_HUMAN (5-349): 1.73e-125: 367: 32.77		TBL1Y_HUMAN (99-430): 2.64e-70: 234: 16.20
+	Hs
		636407 DNJB1_HUMAN (5-347): 8.67e-117: 345: 32.59		TBL1Y_HUMAN (99-430): 2.64e-70: 234: 16.20
+	Hs
		1262170 DNJA4_HUMAN (1-397): 1.01e-159: 456: 73.37		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		243354 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		243668 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		243501 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		POC1A_HUMAN (68-215): 1.37e-12: 71.1: 10.60
+	Hs
		243380 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67
+	Sc
		632985 MAS5_YEAST (1-396): 8.35e-140: 406: 45.37		CDC20_YEAST (319-488): 5.34e-14: 76.2: 18.50
+	Hs
		903434 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		1290534 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		636442 DNJB1_HUMAN (5-347): 8.67e-117: 345: 32.59		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		903579 DJB11_HUMAN (7-330): 1.64e-46: 164: 36.15		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35