HitPredict - High confidence protein-protein interactions

Interactor 1: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	17287208, 15492215
Identification Methods	enzymatic study, in-gel kinase assay
Interaction Type	direct interaction, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001649 - osteoblast differentiation GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 16 others more... GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0005938 - cell cortex GO:0010628 - positive regulation of gene expression GO:0010629 - negative regulation of gene expression GO:0016020 - membrane GO:0019899 - enzyme binding GO:0019901 - protein kinase binding GO:0030027 - lamellipodium GO:0031641 - regulation of myelination GO:0032991 - protein-containing complex GO:0043066 - negative regulation of apoptotic process GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0098978 - glutamatergic synapse
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	480
Hs

1	781

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024