HitPredict

Interactor 1: RBTN2 (P25791)
Rhombotin-2 (Cysteine-rich protein TTG-2) (LIM domain only protein 2) (LMO-2) (T-cell translocation protein 2)
Gene: LMO2

Interactor 2: KANK2 (Q63ZY3)
KN motif and ankyrin repeat domain-containing protein 2 (Ankyrin repeat domain-containing protein 25) (Matrix-remodeling-associated protein 3) (SRC-1-interacting protein) (SIP) (SRC-interacting protein) (SRC1-interacting protein)
Gene: KANK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.80	0.779

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ank_2~LIM
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 158 Hs			1 851
+	Hs
		682040 RBTN1_HUMAN (20-150): 3.92e-39: 131: 55.73		KANK2_HUMAN (1-851): 0: 546: 100.00
+	Hs
		1225018 LMO3_HUMAN (30-156): 6.25e-39: 130: 58.27		KANK2_HUMAN (1-851): 0: 546: 100.00
+	Hs
		965468 LMO4_HUMAN (11-147): 1.13e-38: 130: 42.34		KANK2_HUMAN (1-851): 0: 546: 100.00
+	Hs
		878483 PAXI_HUMAN (3-88): 1.4e-17: 80.4: 19.77		KANK2_HUMAN (1-851): 0: 546: 100.00
+	Hs
		1225085 PDLI7_HUMAN (3-83): 2.61e-15: 73.8: 25.61		KANK2_HUMAN (1-851): 0: 546: 100.00
+	Hs
		1225096 LHX3_HUMAN (92-155): 1.49e-12: 65.7: 23.44		KANK2_HUMAN (1-851): 0: 546: 100.00
+	Hs
		965446 LMO4_HUMAN (11-147): 1.13e-38: 130: 42.34		ASPP2_HUMAN (48-825): 2.24e-67: 245: 15.74
+	Hs
		1250684 LHX3_HUMAN (92-155): 1.49e-12: 65.7: 23.44		BCOR_HUMAN (137-808): 3.95e-66: 243: 15.74
+	Hs
		1115578 LHX4_HUMAN (89-155): 2.33e-11: 62.3: 26.87		ASPP2_HUMAN (48-825): 2.24e-67: 245: 15.74
+	Hs
		895740 LHX2_HUMAN (94-152): 1.6e-11: 62.7: 25.42		BCOR_HUMAN (137-808): 3.95e-66: 243: 15.74
+	Hs
		878516 PAXI_HUMAN (3-88): 1.4e-17: 80.4: 19.77		ANR52_HUMAN (214-793): 7.8e-50: 192: 13.06
+	Hs
		681901 RBTN2_HUMAN (1-158): 5.59e-42: 138: 100.00		EHMT2_HUMAN (74-850): 7.15e-30: 129: 12.72
+	Hs
		1396327 LHX6_HUMAN (7-153): 2.26e-38: 135: 27.70		EHMT2_HUMAN (74-850): 7.15e-30: 129: 12.72
+	Hs
		1311348 LMO3_HUMAN (30-156): 6.25e-39: 130: 58.27		ANKH1_HUMAN (349-849): 2.54e-26: 118: 14.12
+	Hs
		878506 PAXI_HUMAN (3-88): 1.4e-17: 80.4: 19.77		ANKH1_HUMAN (349-849): 2.54e-26: 118: 14.12
+	Hs
		1396315 LHX3_HUMAN (92-155): 1.49e-12: 65.7: 23.44		EHMT2_HUMAN (74-850): 7.15e-30: 129: 12.72
+	Hs
		895779 LHX2_HUMAN (94-152): 1.6e-11: 62.7: 25.42		EHMT2_HUMAN (74-850): 7.15e-30: 129: 12.72
+	Hs
		1447721 PDLI7_HUMAN (3-83): 2.61e-15: 73.8: 25.61		RAI14_HUMAN (710-831): 9e-21: 100: 27.05
+	Hs
		1436922 LHX3_HUMAN (92-155): 1.49e-12: 65.7: 23.44		EHMT1_HUMAN (323-680): 5.13e-15: 81.7: 8.42
+	Hs
		895800 LHX2_HUMAN (94-152): 1.6e-11: 62.7: 25.42		EHMT1_HUMAN (323-680): 5.13e-15: 81.7: 8.42