HitPredict

Interactor 1: AKT1 (P31750)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (AKT1 kinase) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha) (Thymoma viral proto-oncogene)
Gene: AKT1

Interactor 2: H2B1C (Q6ZWY9)
Histone H2B type 1-C/E/G
Gene: H2bc4

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11435472
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 480 Mm			1 126
+	Mm
		682111 AKT1_MOUSE (1-480): 0: 603: 100.00		H2B2B_MOUSE (1-126): 2.21e-54: 168: 98.41
+	Hs
		617926 AKT1_HUMAN (1-480): 0: 598: 98.33		H2B1O_HUMAN (1-126): 2.88e-54: 167: 98.41
+	Hs
		420806 AKT1_HUMAN (1-480): 0: 598: 98.33		H2B1J_HUMAN (1-126): 6.62e-54: 166: 98.41
+	Hs
		681878 AKT1_HUMAN (1-480): 0: 598: 98.33		H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21
+	Hs
		681686 AKT1_HUMAN (1-480): 0: 598: 98.33		H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62
+	Hs
		681937 AKT1_HUMAN (1-480): 0: 598: 98.33		H2B3B_HUMAN (1-126): 8.29e-52: 161: 95.24
+	Hs
		617927 AKT2_HUMAN (1-477): 0: 569: 81.84		H2B1O_HUMAN (1-126): 2.88e-54: 167: 98.41
+	Hs
		420807 AKT2_HUMAN (1-477): 0: 569: 81.84		H2B1J_HUMAN (1-126): 6.62e-54: 166: 98.41
+	Hs
		682181 AKT2_HUMAN (1-477): 0: 569: 81.84		H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21
+	Hs
		682137 AKT2_HUMAN (1-477): 0: 569: 81.84		H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62
+	Hs
		682194 AKT2_HUMAN (1-477): 0: 569: 81.84		H2B3B_HUMAN (1-126): 8.29e-52: 161: 95.24
+	Hs
		241512 KPCD_HUMAN (17-477): 3.11e-150: 445: 32.69		H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21
+	Hs
		241418 KPCB_HUMAN (88-477): 3.99e-145: 432: 42.57		H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21
+	Hs
		408525 KPCB_HUMAN (88-477): 3.99e-145: 432: 42.57		H2B1J_HUMAN (1-126): 6.62e-54: 166: 98.41
+	Hs
		408583 KPCB_HUMAN (88-477): 3.99e-145: 432: 42.57		H2BFS_HUMAN (1-126): 1.03e-53: 166: 97.62
+	Hs
		408591 KPCB_HUMAN (88-477): 3.99e-145: 432: 42.57		H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00
+	Hs
		408624 KPCB_HUMAN (88-477): 3.99e-145: 432: 42.57		H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21
+	Hs
		408565 KPCB_HUMAN (88-477): 3.99e-145: 432: 42.57		H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62
+	Hs
		408585 KPCB_HUMAN (88-477): 3.99e-145: 432: 42.57		H2B1D_HUMAN (1-126): 3.24e-53: 164: 99.21
+	Hs
		408664 KPCB_HUMAN (88-477): 3.99e-145: 432: 42.57		H2B1N_HUMAN (1-126): 3e-53: 164: 99.21