HitPredict

Interactor 1: SPB4 (P25808)
ATP-dependent rRNA helicase SPB4 (EC 3.6.4.13) (Suppressor of PAB1 protein 4)
Gene: SPB4

Interactor 2: NOP12 (Q08208)
Nucleolar protein 12
Gene: NOP12

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30568249, 21825077
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 606 Sc			1 459
+	Sc
		1043300 HAS1_YEAST (6-467): 2.43e-138: 414: 30.98		NOP12_YEAST (1-459): 1.72e-75: 245: 100.00
+	Sc
		682355 SPB4_YEAST (1-606): 7.37e-148: 442: 100.00		NOP13_YEAST (27-400): 8.64e-41: 152: 17.73
+	Hs
		1137086 DDX46_HUMAN (2-597): 1.5e-133: 417: 21.15		SART3_HUMAN (31-408): 3.55e-46: 173: 14.86
+	Sc
		924321 HAS1_YEAST (6-467): 2.43e-138: 414: 30.98		NOP13_YEAST (27-400): 8.64e-41: 152: 17.73
+	Hs
		141299 DDX3X_HUMAN (4-406): 1.33e-114: 358: 24.64		PABP1_HUMAN (175-459): 1.72e-59: 207: 14.58
+	Hs
		141463 DDX3X_HUMAN (4-406): 1.33e-114: 358: 24.64		PABP4_HUMAN (175-459): 2.2e-57: 202: 13.54
+	Hs
		1137122 DDX17_HUMAN (2-463): 6.69e-125: 386: 21.89		SART3_HUMAN (31-408): 3.55e-46: 173: 14.86
+	Dm
		1303431 Q8MZI3_DROME (2-406): 3.77e-123: 385: 26.90		Q8IMX4_DROME (172-437): 2.72e-43: 160: 14.77
+	Ce
		1372527 Q95XY1_CAEEL (7-395): 6.95e-148: 443: 30.69		Q93233_CAEEL (271-364): 1.59e-24: 102: 26.04
+	Ce
		1372528 Q9N3F4_CAEEL (7-395): 6.34e-148: 443: 30.69		Q93233_CAEEL (271-364): 1.59e-24: 102: 26.04
+	Hs
		141495 DDX3X_HUMAN (4-406): 1.33e-114: 358: 24.64		SART3_HUMAN (31-408): 3.55e-46: 173: 14.86
+	Hs
		1152571 DDX17_HUMAN (2-463): 6.69e-125: 386: 21.89		ELAV1_HUMAN (154-360): 6.07e-33: 128: 14.23
+	Hs
		141552 DDX3X_HUMAN (4-406): 1.33e-114: 358: 24.64		PABP2_HUMAN (252-400): 7.94e-43: 155: 25.49
+	Mm
		915297 DDX17_MOUSE (2-439): 5.11e-124: 382: 22.62		TIA1_MOUSE (273-459): 1.48e-33: 131: 12.23
+	Mm
		915325 Q8BTS0_MOUSE (2-454): 5.75e-123: 378: 22.34		TIA1_MOUSE (273-459): 1.48e-33: 131: 12.23
+	Hs
		608614 DDX5_HUMAN (2-446): 1.35e-122: 377: 21.83		ELAV1_HUMAN (154-360): 6.07e-33: 128: 14.23
+	Mm
		1000097 DDX5_MOUSE (2-454): 1.27e-123: 379: 22.34		TIAR_MOUSE (271-459): 9.83e-28: 115: 13.17
+	Hs
		1148533 DDX17_HUMAN (2-463): 6.69e-125: 386: 21.89		SF3B4_HUMAN (269-458): 2.81e-22: 100: 14.56
+	Hs
		1148518 DDX42_HUMAN (2-497): 1.93e-115: 367: 21.08		SF3B4_HUMAN (269-458): 2.81e-22: 100: 14.56
+	Hs
		1137153 DDX47_HUMAN (23-382): 7.97e-54: 191: 34.35		SART3_HUMAN (31-408): 3.55e-46: 173: 14.86