HitPredict

Interactor 1: PROF (P25843)
Profilin (Protein chickadee)
Gene: chic

Interactor 2: Q8IRY0 (Q8IRY0)
Dishevelled associated activator of morphogenesis, isoform B (Dishevelled associated activator of morphogenesis, isoform E) (Dishevelled associated activator of morphogenesis, isoform F) (Dishevelled associated activator of morphogenesis, isoform G)
Gene: DAAM

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19052223
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0051491 - positive regulation of filopodium assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Dm			1 1153
+	Hs
		459769 PROF1_HUMAN (3-126): 1.9e-38: 128: 20.71		DIAP3_HUMAN (27-1125): 0: 718: 23.00
+	Dm
		682717 PROF_DROME (1-126): 5.24e-54: 167: 100.00		DIA_DROME (31-1129): 0: 646: 22.72
+	Hs
		252404 PROF1_HUMAN (3-126): 1.9e-38: 128: 20.71		DIAP1_HUMAN (15-1116): 0: 683: 21.54
+	Hs
		252419 PROF2_HUMAN (3-126): 1.8e-33: 115: 20.71		DIAP1_HUMAN (15-1116): 0: 683: 21.54
+	Hs
		459723 PROF1_HUMAN (3-126): 1.9e-38: 128: 20.71		FMNL2_HUMAN (15-1123): 0: 656: 18.92
+	Dd
		684454 PROF2_DICDI (1-123): 8.28e-42: 136: 39.02		FORH_DICDI (25-1064): 0: 595: 21.26
+	Hs
		337547 PROF1_HUMAN (3-126): 1.9e-38: 128: 20.71		FMNL1_HUMAN (40-1125): 0: 581: 18.61
+	Hs
		337566 PROF2_HUMAN (3-126): 1.8e-33: 115: 20.71		FMNL1_HUMAN (40-1125): 0: 581: 18.61
+	Hs
		459824 PROF1_HUMAN (3-126): 1.9e-38: 128: 20.71		FHOD1_HUMAN (113-1142): 3.85e-177: 553: 14.13
+	Hs
		762514 PROF2_HUMAN (3-126): 1.8e-33: 115: 20.71		FHOD1_HUMAN (113-1142): 3.85e-177: 553: 14.13
+	Hs
		459609 PROF1_HUMAN (3-126): 1.9e-38: 128: 20.71		INF2_HUMAN (108-1137): 1.61e-169: 536: 22.25
+	Hs
		762460 PROF2_HUMAN (3-126): 1.8e-33: 115: 20.71		INF2_HUMAN (108-1137): 1.61e-169: 536: 22.25
+	Ce
		115180 PROF1_CAEEL (1-126): 2.82e-38: 127: 27.27		H2KYI3_CAEEL (42-1143): 4.65e-158: 509: 18.62
+	At
		235329 PRF3_ARATH (1-125): 3.07e-57: 176: 40.77		FH4_ARATH (624-1045): 1.77e-101: 340: 20.43
+	Hs
		258543 PROF1_HUMAN (3-126): 1.9e-38: 128: 20.71		DIAP2_HUMAN (634-1128): 5.11e-116: 388: 25.76
+	At
		235328 PRF2_ARATH (1-125): 2.05e-54: 168: 40.77		FH4_ARATH (624-1045): 1.77e-101: 340: 20.43
+	Hs
		459774 PROF1_HUMAN (3-126): 1.9e-38: 128: 20.71		FMN2_HUMAN (593-1066): 2.84e-98: 346: 22.89
+	Dm
		682733 PROF_DROME (1-126): 5.24e-54: 167: 100.00		CAPU_DROME (605-1070): 2.48e-85: 302: 20.27
+	Sc
		454621 PROF_YEAST (1-126): 4.77e-47: 149: 39.37		BNR1_YEAST (602-1086): 4.3e-84: 302: 20.59
+	Sp
		814715 PROF_SCHPO (1-126): 2.54e-49: 155: 37.01		CDC12_SCHPO (26-535): 3.15e-24: 112: 14.71