Protein: PROF
Profilin

Gene: PROF, PFY1
Organism: Saccharomyces cerevisiae S288C
Interactions: 25
UniProt ID: P07274

Gene Ontology (top 5):
GO:0003785 - actin monomer binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005938 - cell cortex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

454627

ACT
Actin

12

18

Small-scale

0.875

High

454623

BNI1
Protein BNI1

4

20

Small-scale

0.700

High

454621

BNR1
BNI1-related protein 1

3

20

Small-scale

0.647

High

454605

PROF
Profilin

1

2

Small-scale

0.618

High

454611

CAP
Adenylyl cyclase-associated protein

3

2

Small-scale

0.589

High

454608

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.479

High

454619

TSA1
Peroxiredoxin TSA1

1

3

High-throughput

0.479

High

454609

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.458

High

454613

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

454620

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

454612

KCC2
Calcium/calmodulin-dependent protein kinase II

1

2

High-throughput

0.437

High

454614

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

1

High-throughput

0.437

High

454615

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

454616

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.437

High

454617

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

1

High-throughput

0.437

High

454626

SUCA
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial

1

2

High-throughput

0.437

High

454610

BPT1
Bile pigment transporter 1

1

0

High-throughput

0.296

High

454618

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

0

High-throughput

0.282

High

454606

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.261

Low

454607

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.249

Low

454622

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

454624

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.249

Low

454625

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.249

Low

454628

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025