HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: ARHGH (Q96PE2)
Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange factor) (p164-RhoGEF) (p164RhoGEF) (Tumor endothelial marker 4)
Gene: ARHGEF17

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	15778465
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 2063
+	Hs
		684253 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		ARHG2_HUMAN (858-1740): 6.2e-104: 360: 14.74
+	Hs
		684147 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		FGD6_HUMAN (483-1515): 3.52e-100: 357: 15.56
+	Hs
		684142 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		DNMBP_HUMAN (539-1741): 1.41e-93: 338: 15.90
+	Hs
		909883 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ARHG2_HUMAN (858-1740): 6.2e-104: 360: 14.74
+	Hs
		684271 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SPT13_HUMAN (827-1462): 4.88e-96: 327: 14.63
+	Hs
		909717 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		FGD6_HUMAN (483-1515): 3.52e-100: 357: 15.56
+	Mm
		926797 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		ARHG2_MOUSE (858-1740): 3.4e-105: 364: 15.48
+	Hs
		909706 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DNMBP_HUMAN (539-1741): 1.41e-93: 338: 15.90
+	Mm
		910228 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		ARG28_MOUSE (561-1834): 3.74e-92: 335: 13.68
+	Hs
		506563 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		BCR_HUMAN (661-1507): 8.04e-93: 333: 18.96
+	Hs
		909921 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SPT13_HUMAN (827-1462): 4.88e-96: 327: 14.63
+	Hs
		684104 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		ARHGG_HUMAN (853-1410): 1.52e-82: 289: 15.87
+	Hs
		927191 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		DNMBP_HUMAN (539-1741): 1.41e-93: 338: 15.90
+	Mm
		926776 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		ARG28_MOUSE (561-1834): 3.74e-92: 335: 13.68
+	Hs
		164107 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		ARHGA_HUMAN (799-2021): 4.97e-75: 278: 12.40
+	Hs
		506568 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		BCR_HUMAN (661-1507): 8.04e-93: 333: 18.96
+	Hs
		909662 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ARHGG_HUMAN (853-1410): 1.52e-82: 289: 15.87
+	Hs
		927148 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		ARHGG_HUMAN (853-1410): 1.52e-82: 289: 15.87
+	Mm
		926818 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		BCR_MOUSE (855-1495): 2.7e-68: 256: 21.67
+	Mm
		926851 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		ARHG6_MOUSE (1070-1380): 6.44e-69: 251: 20.38