Interactor 1: SYTC (P26639)
Threonine--tRNA ligase 1, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase 1)
Gene: TARS1
Interactor 2: SYTC (P26639)
Threonine--tRNA ligase 1, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase 1)
Gene: TARS1
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31839598 |
| Identification Methods | cross-linking study |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | HGTP_anticodon~HGTP_anticodon, HGTP_anticodon~tRNA-synt_2b, TGS~TGS, TGS~tRNA_SAD, tRNA-synt_2b~tRNA-synt_2b, tRNA_SAD~tRNA_SAD |
| Common GO terms | GO:0000049 - tRNA binding GO:0004829 - threonine-tRNA ligase activity GO:0005524 - ATP binding GO:0005739 - mitochondrion GO:0005829 - cytosol and 3 others more... |
| Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores 
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Last updated: 11Aug2025