HitPredict

Interactor 1: AVR2A (P27037)
Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)
Gene: ACVR2A

Interactor 2: RNF11 (Q9Y3C5)
RING finger protein 11
Gene: RNF11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 154
+	Hs
		690107 AVR2A_HUMAN (1-513): 3.38e-154: 451: 100.00		RN149_HUMAN (66-147): 1.16e-25: 102: 35.37
+	Hs
		1116827 AVR2B_HUMAN (4-513): 3.69e-142: 420: 67.12		RN149_HUMAN (66-147): 1.16e-25: 102: 35.37
+	Hs
		1118393 BMPR2_HUMAN (5-505): 8.65e-116: 367: 32.96		RNF11_HUMAN (1-154): 3.84e-43: 141: 100.00
+	Hs
		787471 TGFR1_HUMAN (60-488): 5.19e-120: 363: 32.31		RNF11_HUMAN (1-154): 3.84e-43: 141: 100.00
+	Hs
		787204 BMR1A_HUMAN (59-488): 2.94e-128: 385: 33.41		RN149_HUMAN (66-147): 1.16e-25: 102: 35.37
+	Hs
		787217 BMR1A_HUMAN (59-488): 2.94e-128: 385: 33.41		RN133_HUMAN (79-147): 1.65e-25: 101: 31.88
+	Hs
		788963 TGFR2_HUMAN (28-493): 8.85e-123: 372: 33.79		RN149_HUMAN (66-147): 1.16e-25: 102: 35.37
+	At
		1375981 CRK39_ARATH (53-502): 7.08e-127: 386: 17.57		ATL75_ARATH (77-141): 9.16e-21: 86.4: 42.42
+	Hs
		1118379 BMPR2_HUMAN (5-505): 8.65e-116: 367: 32.96		RN149_HUMAN (66-147): 1.16e-25: 102: 35.37
+	Hs
		787419 TGFR1_HUMAN (60-488): 5.19e-120: 363: 32.31		GOLI_HUMAN (64-146): 5.88e-26: 103: 25.30
+	Hs
		787425 TGFR1_HUMAN (60-488): 5.19e-120: 363: 32.31		RN149_HUMAN (66-147): 1.16e-25: 102: 35.37
+	Hs
		1048370 ACVR1_HUMAN (47-493): 6.74e-117: 355: 30.27		RN149_HUMAN (66-147): 1.16e-25: 102: 35.37
+	Hs
		787318 ACV1B_HUMAN (2-488): 1.41e-113: 346: 28.41		RN149_HUMAN (66-147): 1.16e-25: 102: 35.37
+	Zm
		9257 A0A1D6EU89_MAIZE (199-492): 2.21e-25: 112: 28.90		B4FHZ7_MAIZE (6-153): 1.74e-27: 106: 21.33