HitPredict

Interactor 1: HIR1 (P32479)
Protein HIR1 (Histone transcription regulator 1)
Gene: HIR1

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.672

Property	Details
Experiments	14651846, 22199229, 22922743, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 840 Sc			1 136
+	Hs
		867850 HIRA_HUMAN (1-838): 1.27e-121: 393: 19.98		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		867853 HIRA_HUMAN (1-838): 1.27e-121: 393: 19.98		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		867878 HIRA_HUMAN (1-838): 1.27e-121: 393: 19.98		H32_HUMAN (1-136): 6.6e-61: 185: 88.97
+	Mm
		952748 HIRA_MOUSE (1-838): 4.05e-118: 384: 20.13		H33_MOUSE (1-136): 1.25e-61: 187: 90.44
+	At
		886471 HIRA_ARATH (1-837): 7.08e-114: 372: 21.30		H33_ARATH (1-136): 4.81e-62: 187: 87.50
+	Hs
		828179 HIRA_HUMAN (1-838): 1.27e-121: 393: 19.98		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Hs
		934716 CAF1B_HUMAN (1-553): 1.51e-83: 279: 21.25		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		952307 CAF1B_HUMAN (1-553): 1.51e-83: 279: 21.25		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		1024551 CAF1B_HUMAN (1-553): 1.51e-83: 279: 21.25		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Hs
		1024562 CAF1B_HUMAN (1-553): 1.51e-83: 279: 21.25		H32_HUMAN (1-136): 6.6e-61: 185: 88.97
+	Dm
		53056 A1Z898_DROME (1-649): 3.22e-81: 278: 19.22		H3_DROME (1-136): 6.6e-61: 185: 88.97
+	Sc
		902046 CAC2_YEAST (1-447): 1.34e-76: 258: 19.28		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Sc
		730914 CAC2_YEAST (1-447): 1.34e-76: 258: 19.28		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04
+	Hs
		935038 PHIP_HUMAN (110-394): 4.79e-37: 153: 11.03		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		952500 PHIP_HUMAN (110-394): 4.79e-37: 153: 11.03		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		1174607 PHIP_HUMAN (110-394): 4.79e-37: 153: 11.03		H32_HUMAN (1-136): 6.6e-61: 185: 88.97
+	Hs
		934796 TAF5_HUMAN (129-432): 8.1e-21: 100: 17.04		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Sc
		690885 HIR2_YEAST (286-838): 1.31e-24: 112: 15.25		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Hs
		828320 PHIP_HUMAN (110-394): 4.79e-37: 153: 11.03		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Sc
		690871 HIR2_YEAST (286-838): 1.31e-24: 112: 15.25		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04