HitPredict

Interactor 1: RPN12 (P32496)
26S proteasome regulatory subunit RPN12 (Nuclear integrity protein 1)
Gene: RPN12

Interactor 2: PRS10 (P53549)
26S proteasome subunit RPT4 (26S protease subunit SUG2) (Proteasomal cap subunit)
Gene: RPT4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	11805826, 16554755, 16429126, 37968396
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 274 Sc			1 437
+	Hs
		819789 PSMD8_HUMAN (16-274): 3.08e-101: 300: 31.27		PRS8_HUMAN (43-437): 1.18e-135: 397: 41.29
+	Hs
		819792 PSMD8_HUMAN (16-274): 3.08e-101: 300: 31.27		PRS10_HUMAN (51-437): 1.51e-129: 381: 67.70
+	At
		1352165 PSD8A_ARATH (2-274): 3.08e-93: 277: 28.06		PRS4A_ARATH (19-428): 3e-135: 397: 37.74
+	Hs
		819788 PSMD8_HUMAN (16-274): 3.08e-101: 300: 31.27		PRS4_HUMAN (27-428): 6.56e-126: 373: 38.24
+	Sc
		691495 RPN12_YEAST (1-274): 3.71e-102: 300: 100.00		PRS8_YEAST (73-437): 2.68e-99: 304: 44.89
+	Sc
		691456 RPN12_YEAST (1-274): 3.71e-102: 300: 100.00		PRS7_YEAST (116-436): 9.22e-93: 289: 46.89
+	Hs
		798610 PSMD8_HUMAN (16-274): 3.08e-101: 300: 31.27		PRS6B_HUMAN (1-123): 4.23e-09: 60.2: 8.03